Results 151 to 160 of about 520,434 (259)

The effect of mobile phone messaging to support COVID-19 vaccination in Colombia: A randomized controlled clinical trial. [PDF]

PLOS Glob Public Health
Vecino-Ortiz AI, Guzman-Tordecilla DN, Maniar V, Agudelo-Londoño S, Aya Pastrana N, Franco Suárez O, Rodríguez Patarroyo M, Mejia-Rocha M, Chavez Chamorro M, Ortiz Hoyos JL, Trujillo AJ, Ali J, Gibson DG.   +12 more
europepmc   +1 more source

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

Benign maculopapular rash following dengue vaccination with Butantan-DV: a case series. [PDF]

An Bras Dermatol
Carvalho TH, Monteiro Neto AJO, Bonini IFDSM, Oliveira MZM, Jorge MFS, Miot HA.   +5 more
europepmc   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Correction: Determinants of parental vaccine hesitancy in Canada: results from the 2017 Childhood National Immunization Coverage Survey

BMC Public Health
Ruoke Chen, Mireille Guay, Nicolas L. Gilbert, Eve Dubé, Holly O. Witteman, Hina Hakim   +5 more
doaj   +1 more source

Simulating targeted vaccination strategies with network-based and agent-based models: A scoping review. [PDF]

PLOS Glob Public Health
Al-Amery A, Al-Qudah R, Herrera-Diestra J, Ertem MZ.   +3 more
europepmc   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Analysis of an AI-powered system for vaccination screening, monitoring, and management in adults aged 50 and above. [PDF]

Front Public Health
Tao L, Zhang J, Bai Y, Li S, Jia B, Ma J, Qi Z, Yang Z, Wang P, Wang X, Zheng Z, Qiao Y.   +11 more
europepmc   +1 more source

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu, Ming Yi, Ji Chen, Zeda Zhao, Ruocen Liao, Yingnan Wang, Shengtao Hu, Jun Ding, Ronghua Zhao, William Jia, Yinan Shen, Yongchang Wei, Kongming Wu, Zhijun Dai   +13 more
wiley   +1 more source

Beyond Awareness: The Critical Need for Actionable Strategies to Bridge the Knowledge-Practice Gap in Hepatitis B Prevention. [PDF]

Health Sci Rep
Qingfei K, Wen X.
europepmc   +1 more source