Results 231 to 240 of about 1,370,088 (427)

Living Microalgae‐Based Magnetic Microrobots for Calcium Overload and Photodynamic Synergetic Cancer Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
A magnetic microrobot fabricated by Spirulina platensis is proposed to accumulate in tumor regions and generate in situ high calcium concentration and sufficient oxygen. These characteristics of the microrobot present a strategy for triggering calcium overload therapy and chlorophyll‐mediated photodynamic therapy, and such combination resulted in a ...
Shuai Jiang   +12 more
wiley   +1 more source

Cholesterol Functionalized Nanoparticles Are Effective against Helicobacter pylori, the Gastric Bug: A Proof‐of‐Concept Study

open access: yesAdvanced Healthcare Materials, EarlyView.
Helicobacter pylori gastric infection is widespread and recurrency is common, fuelled by bacterial resistance to antibiotics. Therefore, specific and noninducing resistance alternative treatments are an urgent need. Taking advantage of this gastric pathogen auxotrophy for cholesterol, a “trojan horse” strategy for H.
Ana Sofia Pinho   +6 more
wiley   +1 more source

Estimates and determinants of HPV non-vaccination in 14-year-old Canadians: Results from the childhood national immunization coverage survey, 2019

open access: yesHuman Vaccines & Immunotherapeutics
Human papillomavirus (HPV) infections, the most common sexually transmitted infections, are associated with various health outcomes including anogenital warts and cancers.
Aranee Sathiyamoorthy   +2 more
doaj   +1 more source

A Novel 3D High‐Throughput Phenotypic Drug Screening Pipeline to Identify Drugs with Repurposing Potential for the Treatment of Ovarian Cancer

open access: yesAdvanced Healthcare Materials, EarlyView.
Ovarian cancer's high recurrence and therapy resistance demand new strategies. A high‐throughput drug screening pipeline using 3D spheroids, which showed poor concordance with 2D models, identified rapamycin as a promising candidate. In combination with cisplatin, rapamycin demonstrated significant in vitro and in vivo efficacy, highlighting the ...
Nazanin Karimnia   +9 more
wiley   +1 more source

ANTIBODY RESPONSE OF HUMAN BEINGS FOLLOWING VACCINATION WITH INFLUENZA VIRUSES [PDF]

open access: bronze, 1942
George K. Hirst   +3 more
openalex   +1 more source

Unlocking the Gates: A Novel Diagnostic Molecule for Quantifying Efflux Levels in Gram‐Positive Bacteria

open access: yesAdvanced Healthcare Materials, EarlyView.
Efflux‐mediated resistance compromises antibiotic efficacy, yet rapid detection remains elusive. This study presents a novel phenazinium‐based diagnostic molecule for quantifying bacterial efflux levels in Gram‐positive pathogens. The optimized compound enables precise, real‐time efflux assessment using fluorescence and colorimetric techniques ...
Mrunal Patil   +15 more
wiley   +1 more source

Small interface changes have dramatic impacts: How mandatory fields in electronic medical records increased pertussis vaccination rates in Australian obstetric patients [PDF]

open access: yes, 2019
Introduction: Electronic health records have been widely introduced into clinical practice. The aim of this study was to determine whether a small interface change could improve compliance with a key quality indicator, namely antenatal pertussis ...
Orefice, Roberto, Quinlivan, Julie
core   +1 more source

Co‐Delivery of Multiple Toll‐Like Receptor Agonists and Avian Influenza Hemagglutinin on Protein Nanoparticles Enhances Vaccine Immunogenicity and Efficacy

open access: yesAdvanced Healthcare Materials, EarlyView.
This research highlights a novel application of protein nanoparticles to effectively modulate the strength, breadth, and bias of an immune response against influenza virus. Nanoparticles precisely co‐delivering antigen (H5) and multiple adjuvants (CpG and FliCc) present a way to improve and direct prophylactic immune responses which can be applicable ...
Aaron Ramirez   +6 more
wiley   +1 more source

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