LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Herpes zoster knowledge, attitudes, and herpes zoster vaccine acceptability among patients in a tertiary hospital and dermatologists in the Philippines: A cross-sectional study. [PDF]
Lim KK, Lo CBO, Batac MCFR.
europepmc +1 more source
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang +10 more
wiley +1 more source
Prevalence, spatial patterns and determinants of zero-dose vaccination among children aged 12-23 months in Sub-Saharan Africa: A multilevel spatial analysis. [PDF]
Tamir TT, Agimas MC, Angaw DA.
europepmc +1 more source
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang +16 more
wiley +1 more source
Association between vaccination prescription program and herpes zoster vaccine knowledge, intention, and coverage among residents aged ≥50 in Zhejiang Province: Repeated cross-sectional surveys. [PDF]
Yan X, Zhang X, Xu Y, Xu J.
europepmc +1 more source
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Vaccines at the Heart of Hepatitis Elimination: Insights From the ESCMID Study Group for Viral Hepatitis (ESGVH). [PDF]
Săndulescu O +5 more
europepmc +1 more source

