Results 271 to 280 of about 1,220,751 (338)

Structural Characterization and AI‐Enhanced Modeling of a Broadly Neutralizing Camelid Antibody Against SARS‐CoV‐2 Variants

Advanced Therapeutics, EarlyView.
This study characterizes a camelid antibody (B10) with potent neutralizing activity against SARS‐CoV‐2 Wildtype and Omicron variants. Through binding assays, epitope mapping, pseudovirus neutralization, and AI‐driven modeling, the antibody is shown to target conserved RBD regions in a closed Spike conformation.
Katja Hanack, Urszula Orzeł, Anja Schlör, Sourabh Mehta, Anandi Krishnan, Slawomir Filipek, Rushika Patel, Madhvi Joshi, Markus Hoffmann, Stefan Pöhlmann, Chaitanya Joshi, Dorian Liepmann, Ramasamy Paulmurugan, Venkatesan Renugopalakrishnan   +13 more
wiley   +1 more source

Hybrid, infection- and vaccination-induced protection against laboratory- confirmed SARS-CoV-2 infection in a European multi-centre prospective cohort of healthcare workers, 2021-2024. [PDF]

BMC Med
Rojas-Castro M, Mulchandani R, Brolin K, Makarić ZL, Uusküla A, Bergin C, Fleming C, Bonfanti P, Murri R, Zvirbulis V, Zavadska D, Szuldrzynski K, Gaio V, Popescu CP, Craiu M, Hrișcă RM, Cisneros M, Latorre-Millán M, Petrović G, Lohur L, McGrath J, Ferguson L, Spolti A, De Gaetano Donati K, Abolina I, Gravele D, Machado A, Florescu SA, Lazar M, Subirats P, Clusa L, Sarajlić G, Sui J, Kenny C, Santangelo R, Krievins D, Barzdina EA, Henriques CV, Kosa AG, Pohrib SM, Miron VD, Muñoz-Almagro C, Milagro AM, Bacci S, Savulescu C, VEBIS HCW VE study group.   +45 more
europepmc   +1 more source

Flavin Biosynthesis Enhances Extracellular Electron Transfer in Bioengineered Escherichia coli

Advanced Science, EarlyView.
Microbial electronics are promising for energy, sensing, environmental, and synthesis applications. E. coli are engineered with extracellular electron transfer (EET) pathways from a microbe that naturally produces current to enable bioelectronics based on E. coli.
Mohammed Mouhib, Melania Reggente, Hanxuan Wang, Charlotte Roullier, Ardemis A. Boghossian   +4 more
wiley   +1 more source

Vaccination in the post-COVID era: lessons to be learned in Latin America. [PDF]

Front Immunol
Del Carpio-Orantes L, Zambrano-Sánchez G.   +1 more
europepmc   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Socioeconomic Barriers to COVID-19 Booster Vaccination in Southern Italy: A Retrospective Study to Evaluate Association with the Social and Material Vulnerability Index in Apulia. [PDF]

Vaccines (Basel)
Bartolomeo N, Lorusso L, Maldera N, Trerotoli P.   +3 more
europepmc   +1 more source

Vaccine hesitancy - vaccine refusal.

Turk pediatri arsivi, 2019
openaire   +2 more sources

Obesity‐Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis

Advanced Science, EarlyView.
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang, Chong Yang, Dayuan Luo, Pingting Liu, Zhen Zeng, Weilin Peng, Dongzi Peng, Hao Su, Xiaoxiong Xiao, Haiqin Wang, Xin Jin   +10 more
wiley   +1 more source

Predictors of COVID-19 vaccination intention among students in Ghana: An application of the Health Belief Model and Theory of Planned Behaviour. [PDF]

PLOS Glob Public Health
Ahmed H, Gohoho M, Bosoka SA, Agyemang GS, Ziema SA, Alorwu J, Annobil I, Charles-Unadike VO.   +7 more
europepmc   +1 more source

Vaccination

BMJ
openaire   +3 more sources