Results 171 to 180 of about 9,622 (181)
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Clearance of Immunodeficiency-associated Vaccine-derived Poliovirus Infection With Pocapavir

Pediatric Infectious Disease Journal, 2020
Pocapavir exhibits antiviral activity against both polio and nonpolio enteroviruses. There is limited experience of the use of this investigational drug in young children with enteroviral infection. We describe the successful clearance of prolonged immunodeficiency-associated vaccine-derived type 3 poliovirus infection by pocapavir in an infant with ...
Julie, Copelyn   +10 more
openaire   +2 more sources

Vaccine-derived poliovirus (VDPV): Impact on poliomyelitis eradication

Vaccine, 2009
The live attenuated strains used in the oral poliovirus (OPV) have been the main tool in the WHO polio eradication programme. However, these strains replicate in the human gut and are excreted for several weeks after immunisation. During this period, the attenuating mutations in the vaccine strains can rapidly revert.
openaire   +2 more sources

Progress with inactivated poliovirus vaccines derived from the Sabin strains.

Developments in biologicals, 2002
To produce a safe and effective inactivated poliovirus vaccine (IPV), we have developed S-IPV using Vero cells infected with the Sabin strains in a semi-production scale. All production steps including virus culture on microcarrier beads were highly reproducible.
Y, Doi   +10 more
openaire   +2 more sources

Poliomyelitis outbreaks caused by circulation of the vaccine-derived poliovirus

International Journal of Surgery, 2022
Farid Rahimi, Amin Talebi Bezmin Abadi
openaire   +2 more sources

Poliovirus Vaccine and Vaccine-Derived Polioviruses

New England Journal of Medicine, 2010
Lester M, Shulman   +2 more
openaire   +3 more sources

Epidemiology and vaccination strategies against type-2 vaccine -derived poliovirus

2023
In 1988, the World Health Assembly passed a resolution to eradicate poliomyelitis, a disease which was endemic in 125 countries and paralyzed 350,000 children per year. Primarily through the large-scale use of oral poliovirus vaccine (OPV), two of the three wild poliovirus (WPV) serotypes (types 2 and 3) have been declared as globally eradicated and ...
openaire   +1 more source

Vaccine-derived poliovirus type 3 emergence in Guinea, 2024

The Lancet Infectious Diseases
Martin, Faye   +24 more
openaire   +2 more sources

[Prevention of vaccine derived poliovirus transmission].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2009
openaire   +1 more source

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