Results 101 to 110 of about 2,114,452 (380)

Safety, tolerability, and immunogenicity of a novel 4-antigen Staphylococcus aureus vaccine (SA4Ag) in healthy Japanese adults

Human Vaccines & Immunotherapeutics, 2018
A novel Staphylococcus aureus 4-antigen vaccine (SA4Ag) is under development, comprising capsular polysaccharide serotypes 5 and 8 (CP5 and CP8) conjugated to CRM197, recombinant protein clumping factor A (rmClfA), and recombinant manganese transporter ...
Megumi Inoue, Takuma Yonemura, James Baber, Yasuko Shoji, Masakazu Aizawa, David Cooper, Joseph Eiden, William C. Gruber, Kathrin U. Jansen, Annaliesa S. Anderson, Alejandra Gurtman   +10 more
doaj   +1 more source

COVID-19 vaccine development: milestones, lessons and prospects

Signal Transduction and Targeted Therapy, 2022
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern (VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 vaccines mainly include inactivated, live attenuated, viral vector, protein subunit,
Maochen Li, Han Wang, Lili Tian, Zehan Pang, Qing-yi Yang, Tianqi Huang, Junfen Fan, Lihua Song, Y. Tong, Huahao Fan   +9 more
semanticscholar   +1 more source

Heterogeneity of Rheumatoid Arthritis‐Associated Interstitial Lung Disease by Longitudinal Forced Vital Capacity Trajectory and Associations with Disease Outcomes

Arthritis Care &Research, Accepted Article.
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis‐associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999‐2021. RA‐ILD patients were
Bryant R. England, Yangyuna Yang, Punyasha Roul, Tate M. Johnson, Scott M. Matson, Grant W. Cannon, Brian C. Sauer, Jeffrey R. Curtis, Joshua F. Baker, Ted R. Mikuls   +9 more
wiley   +1 more source

The global burden of cholera

Bulletin of the World Health Organization, 2012
OBJECTIVE: To estimate the global burden of cholera using population-based incidence data and reports. METHODS: Countries with a recent history of cholera were classified as endemic or non-endemic, depending on whether they had reported cholera cases in ...
Mohammad Ali, Anna Lena Lopez, Young Ae You, Young Eun Kim, Binod Sah, Brian Maskery, John Clemens   +6 more
doaj  

Development of flow cytometry based adherence assay for Neisseria gonorrhoeae using 5′-carboxyfluorosceinsuccidyl ester

BMC Microbiology, 2019
Background Neisseria gonorrhoeae is an obligate human pathogen and its adherence to host cells is essential for its pathogenesis. Gonococcal adherence assays are based on the enumeration of bacteria attached to human cells on solid media.
Sidharath Dev Thakur, Milan Obradovic, Jo-Anne R. Dillon, Siew Hon Ng, Heather L. Wilson   +4 more
doaj   +1 more source

Infection-acquired versus vaccine-acquired immunity in an SIRWS model [PDF]

, 2017
Despite high vaccine coverage, pertussis has re-emerged as a public health concern in many countries. One hypothesis posed for re-emergence is the waning of immunity.
Campbell, Patricia T, Frascoli, Federico, Hughes, Barry D, Leung, Tiffany, McCaw, James M   +4 more
core   +2 more sources

Vaccine and Vaccination: On Field Research

Vaccines, 2022
Historically, vaccinations have enabled the eradication, elimination, and control of many debilitating diseases [...]
Francesca Gallè, Christian Napoli
openaire   +3 more sources

High Rates of COVID-19 Vaccine Hesitancy and Its Association with Conspiracy Beliefs: A Study in Jordan and Kuwait among Other Arab Countries

Vaccines, 2021
Vaccination could be an effective strategy for slowing the spread of the current coronavirus disease 2019 (COVID-19) pandemic. Vaccine hesitancy could pose a serious problem for COVID-19 prevention, due to the spread of misinformation surrounding the ...
Malik Sallam, D. Dababseh, H. Eid, Kholoud Al-Mahzoum, A. Al-Haidar, D. Taim, A. Yaseen, N. Ababneh, F. Bakri, A. Mahafzah   +9 more
semanticscholar   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Systems serology-based comparison of humoral immune responses induced by liposome or aluminum hydroxide adjuvanted SARS-CoV-2 spike protein

Scientific Reports
Adjuvants play a crucial role in enhancing vaccine-induced immune responses by shaping the magnitude and quality of humoral and cellular immunity.
Soo Ji Kim, Taewoo Kim, Satyanarayana Bejjani, Mi Sun Kim, Jung Hyuk Lee, Yuna Shin, Sun-Je Woo, Beom Min Cheon, Doyoung Kim, Sumin Lee, Eunjin Cho, Junhyeon Lee, Ruchirkumar Pansuriya, Wook-Jin Park, Gaurav Pandey, Ravi Ganapathy, Jung-Ah Choi, Ju Yeon Park, Deok Ryun Kim, Cheol-Heui Yun, Jae Seung Yang, Byoung-Shik Shim, Manki Song   +22 more
doaj   +1 more source