Results 81 to 90 of about 1,582,509 (353)

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Paperless registration during survey enumerations and large oral cholera mass vaccination in Zanzibar, the United Republic of Tanzania

Bulletin of the World Health Organization
PROBLEM: Field trials require extensive data preparation and complex logistics. The use of personal digital assistants (PDAs) can bypass many of the traditional steps that are necessary in a paper-based data entry system.
Mohammad Ali, Jaqueline L Deen, Ahmed Khatib, Godwin Enwere, Lorenz von Seidlein, Rita Reyburn, Said Mohammed Ali, Na Yoon Chang, Valérie Perroud, Frédérique Marodon, Abdul A Saleh, R Hashim, Anna Lena Lopez, James Beard, Benedikt N Ley, Kamala Thriemer, Mahesh K Puri, Binod Sah, Mohamed Saleh Jiddawi, John D Clemens   +19 more
doaj   +1 more source

Conducting a phase III clinical trial in children during the COVID- 19 pandemic: Experience and lessons learnt from a clinical research facility of Nepal

Human Vaccines & Immunotherapeutics, 2023
Clinical trials in humans are vital to test safety and efficacy of new interventions and are accompanied with the complexity of related regulatory guidelines, stringent time frame and financial burden particularly when participants are children ...
Ram Hari Chapagain, Jessica Maharjan, Santosh Adhikari, Prabhat Thapa, Kshitij Kunwar, Bishnu Rath Giri, Nisha Jyoti Shrestha, Anil Kumar Shrestha, Sanjeet Kumar Shrestha, Suresh Man Tamang, Haeun Cho, Eun Lyeong Park, Jiyoung Lee, Jinae Lee, Deok Ryun Kim, Jae Seung Yang, Tarun Saluja, Anh Wartel, Julia Lynch, Katerina Rok Song   +19 more
doaj   +1 more source

Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape

Nature reviews. Immunology, 2021
Where 2020 saw the development and testing of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at an unprecedented pace, the first half of 2021 has seen vaccine rollout in many countries.
J. Tregoning, Katie E. Flight, Sophie Higham, Ziyin Wang, B. F. Pierce   +4 more
semanticscholar   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

VACCINATION [PDF]

The American Journal of the Medical Sciences, 1886
n ...
openaire   +2 more sources

Nonlytic Fc-fused IL-7 synergizes with Mtb32 DNA vaccine to enhance antigen-specific T cell responses in a therapeutic model of tuberculosis

, 2013
Improvement to the immunogenicity of DNA vaccines was evaluated in a Mycobacterium tuberculosis (MTB) infection mouse model examining the combined effects of nonlytic Fc-fused IL-7 DNA (IL-7-nFc) and Flt3-ligand fused Mtb32 (F-Mtb32) DNA.
조상래
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Building resilient and response-ready influenza vaccination programs for pandemic preparedness: a comparative analysis from five middle-income countries

BMC Health Services Research
Influenza vaccination programs are critical in reducing the morbidity and mortality from seasonal influenza and bolstering pandemic preparedness. However, there is a notable lack of information about the factors contributing to resilient and response ...
Marissa Malchione, Theresa Sommers, Meredith Dockery, Vishakh Unnikrishnan, Alison Mack, Kathryn L. Hopkins, Angus Thomson, Ben McCormick, Joel Tinkler, Cassidy Howell, Nick Boehman, Danielle Countryman, Marie Mazur, Malembe Ebama, Stacey Knobler   +14 more
doaj   +1 more source

Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients.

Journal of the American Medical Association (JAMA), 2021
Antibody Response to 2-Dose SARS-CoV-2 mRNA Vaccine Series in Solid Organ Transplant Recipients In contrast to immunocompetent participants in vaccine trials,1,2 a low proportion (17%) of solid organ transplant recipients mounted a positive antibody ...
B. Boyarsky, William Werbel, R. Avery, A. Tobian, A. Massie, D. Segev, J. Garonzik‐Wang   +6 more
semanticscholar   +1 more source