Results 61 to 70 of about 1,015,995 (302)

Vaccines and Vaccination

, 2015
Livestock vaccines aim to increase livestock product and improve the health and welfare of livestock animals in a cost-efficient manner and prevent disease transmission. Successful livestock vaccines have been generated for pathogens including bacterial, viral, protozoan, and multicellular pathogens.
openaire   +2 more sources

Malaria vaccine research and development: the role of the WHO MALVAC committee. [PDF]

, 2013
The WHO Malaria Vaccine Advisory Committee (MALVAC) provides advice to WHO on strategic priorities, activities and technical issues related to global efforts to develop vaccines against malaria.
Vasee S Moorthy, Graham V Brown, Geoffrey AT Targett, Targett, Geoffrey AT, Brown, GV, Moorthy, Vasee S, Brown, Graham V, Geoffrey AT Targett, Moorthy, VS, Targett, GA   +9 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Conducting a phase III clinical trial in children during the COVID- 19 pandemic: Experience and lessons learnt from a clinical research facility of Nepal

Human Vaccines & Immunotherapeutics, 2023
Clinical trials in humans are vital to test safety and efficacy of new interventions and are accompanied with the complexity of related regulatory guidelines, stringent time frame and financial burden particularly when participants are children ...
Ram Hari Chapagain, Jessica Maharjan, Santosh Adhikari, Prabhat Thapa, Kshitij Kunwar, Bishnu Rath Giri, Nisha Jyoti Shrestha, Anil Kumar Shrestha, Sanjeet Kumar Shrestha, Suresh Man Tamang, Haeun Cho, Eun Lyeong Park, Jiyoung Lee, Jinae Lee, Deok Ryun Kim, Jae Seung Yang, Tarun Saluja, Anh Wartel, Julia Lynch, Katerina Rok Song   +19 more
doaj   +1 more source

A review of the tolerability of the candidate TB vaccine, MVA85A compared with BCG and Yellow Fever vaccines, and correlation between MVA85A vaccine reactogenicity and cellular immunogenicity [PDF]

, 2012
© 2012 Elsevier Ltd. All rights reservedBackground: The development of a new, more effective vaccine against tuberculosis (TB) for use in healthy and HIV-infected adults, children and infants, remains a global health priority.
Sander, C, Angela M Minassian, Nicola Williams, Lawrie, AM, Alison M Lawrie, Rowland, R, Poulton, ID, Rosalind Rowland, Brittain, N, Pathan, AA, David W Porter, Minassian, AM, Helen McShane, Iman Satti, Ansar A Pathan, Ian D Poulton, Nathaniel Brittain, Williams, N, Clare Sander, Porter, DW, Satti, I, McShane, H   +21 more
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

The global burden of cholera

Bulletin of the World Health Organization, 2012
OBJECTIVE: To estimate the global burden of cholera using population-based incidence data and reports. METHODS: Countries with a recent history of cholera were classified as endemic or non-endemic, depending on whether they had reported cholera cases in ...
Mohammad Ali, Anna Lena Lopez, Young Ae You, Young Eun Kim, Binod Sah, Brian Maskery, John Clemens   +6 more
doaj  

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Calibration of a serum reference standard for Group B streptococcal polysaccharide conjugate vaccine development using surface plasmon resonance

npj Vaccines, 2023
Group B streptococcus (GBS) is a leading cause of neonatal morbidity and mortality worldwide. Development of a maternal vaccine to protect newborns through placentally transferred antibody is considered feasible based on the well-established relationship
Alexandre Esadze, Christopher D. Grube, Sabine Wellnitz, Suddham Singh, Ha H. Nguyen, Michelle A. Gaylord, Aiping Zhu, Alexey Gribenko, Charles Y. Tan, Annaliesa S. Anderson, Raphael Simon   +10 more
doaj   +1 more source