Results 51 to 60 of about 1,015,995 (302)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Paperless registration during survey enumerations and large oral cholera mass vaccination in Zanzibar, the United Republic of Tanzania

Bulletin of the World Health Organization
PROBLEM: Field trials require extensive data preparation and complex logistics. The use of personal digital assistants (PDAs) can bypass many of the traditional steps that are necessary in a paper-based data entry system.
Mohammad Ali, Jaqueline L Deen, Ahmed Khatib, Godwin Enwere, Lorenz von Seidlein, Rita Reyburn, Said Mohammed Ali, Na Yoon Chang, Valérie Perroud, Frédérique Marodon, Abdul A Saleh, R Hashim, Anna Lena Lopez, James Beard, Benedikt N Ley, Kamala Thriemer, Mahesh K Puri, Binod Sah, Mohamed Saleh Jiddawi, John D Clemens   +19 more
doaj   +1 more source

پایداری و چرخش ارگانی ویروس تیپ o بیماری تب برفکی در خوکچه هندی [PDF]

Archives of Razi Institute, 2010
از آنجایی که خوکچه هندی به عنوان بهترین حیوان آزمایشگاهی حساس به ویروس بیماری تب برفکی مطرح شده است، مقدار یک میلی لیتر از ویروس تب برفکی تیپ O با غلظت TCID50 106-5/106به ناحیه کف پای 10 سر خوکچه هندی (سمت راست) به روش داخل پوستی تزریق شد.
محمد اسلام پناه, همایون مهروانی, محمدحسن حبل الورید, ح. ایزدی, م. ستوده, ف. جیرانی, ف. طالب لو   +6 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

VACCINATION [PDF]

The American Journal of the Medical Sciences, 1886
n ...
openaire   +2 more sources

Varicella Breakthrough Infection and Vaccine Effectiveness in Taiwan

, 2012
We performed this nationwide retrospective investigation among the recipients of varicella vaccine to evaluate the breakthrough varicella infection rate, factors associated with breakthrough infection and the vaccine effectiveness.
HUANG, WEN-CHAN;HUANG, LI-MIN;CHANG, I-SHOU;TSAI, FANG-YU;CHANG, LUAN-YIN, 黃文嬋;黃立民;張憶壽;蔡芳榆;張鑾英   +1 more
core   +1 more source

Assessment of parental perception of malaria vaccine in Tanzania [PDF]

, 2015
Clinical trials of the RTS,S malaria vaccine have completed Phase III and the vaccine is on track for registration. Before making decisions about implementation, it is essential to prepare the ground for introducing the vaccine by assessing awareness and
Marcel Tanner, Idda Romore, Hassan Mshinda, Abdulla, Salim, Romore, Idda, Ali Mohamed Ali, Salim Abdulla, Semali, Innocent, Ali, Ali Mohamed, Innocent Semali, Mshinda, Hassan, Tanner, Marcel, Mshinda H, Ali AM, Semali I, Abdulla S, Tanner M, Romore I   +17 more
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Building resilient and response-ready influenza vaccination programs for pandemic preparedness: a comparative analysis from five middle-income countries

BMC Health Services Research
Influenza vaccination programs are critical in reducing the morbidity and mortality from seasonal influenza and bolstering pandemic preparedness. However, there is a notable lack of information about the factors contributing to resilient and response ...
Marissa Malchione, Theresa Sommers, Meredith Dockery, Vishakh Unnikrishnan, Alison Mack, Kathryn L. Hopkins, Angus Thomson, Ben McCormick, Joel Tinkler, Cassidy Howell, Nick Boehman, Danielle Countryman, Marie Mazur, Malembe Ebama, Stacey Knobler   +14 more
doaj   +1 more source

Challenges and opportunities in setting up a phase III vaccine clinical trial in resource limited settings: Experience from Nepal

Human Vaccines & Immunotherapeutics, 2021
Clinical trials are complicated, time-consuming and costly. From the initial screening, informed consent and recruitment of the participants’ to study completion, the sponsor must undertake a wide array of complex and closely monitored operations ...
Tarun Saluja, Bishnu Rath Giri, Shipra Chaudhary, Dipesh Tamrakar, Piush Kanodia, Sonali Palkar, Sridhar Vemula, Suchada Chinaworapong, Bomi Kim, Birendra Prasad Gupta, Sue Kyoung Jo, Sanet Aspinall, Ganesh Kumar Rai, Duncan Steele, Jerome H. Kim, T. Anh Wartel, Sushant Sahastrabuddhe   +16 more
doaj   +1 more source