Results 41 to 50 of about 1,582,509 (353)

mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant

medRxiv, 2021
Recent surveillance has revealed the emergence of the SARS-CoV-2 Omicron variant (BA.1/B.1.1.529) harboring up to 36 mutations in spike protein, the target of vaccine-induced neutralizing antibodies.
W. Garcia-Beltran, Kerri J. St. Denis, Angelique Hoelzemer, Evan C. Lam, Adam D Nitido, M. Sheehan, C. Berríos, Onosereme Ofoman, Christina C. Chang, B. Hauser, J. Feldman, Alex Roederer, D. Gregory, M. Poznansky, A. Schmidt, A. Iafrate, V. Naranbhai, A. Balazs   +17 more
semanticscholar   +1 more source

The marginal willingness-to-pay for attributes of a hypothetical HIV vaccine [PDF]

, 2012
This paper estimates the marginal willingness-to-pay for attributes of a hypothetical HIV vaccine using discrete choice modeling. We use primary data from 326 respondents from Bangkok and Chiang Mai, Thailand, in 2008–2009, selected using purposive ...
Newman, Peter A., Newman, PA, P. A. Newman, S. Roungprakhon, Newman, P.A., Cameron, MP, Scarpa, R., Scarpa, R, Scarpa, Riccardo, Roungprakhon, S, Cameron, Michael P., Cameron, Michael Patrick, Cameron, M.P., Roungprakhon, S., Roungprakhon, Surachet, M. P. Cameron   +15 more
core   +1 more source

Development of an inactivated vaccine candidate for SARS-CoV-2

Science, 2020
Vaccine candidate tested in monkeys Global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an urgent race to develop a vaccine. Gao et al.
Q. Gao, L. Bao, H. Mao, Lin Wang, Kangwei Xu, Minnan Yang, Ya-Jing Li, Ling Zhu, Nan Wang, Zhe Lv, Hong Gao, Xiaoqin Ge, B. Kan, Yalin Hu, Jiangning Liu, Fang Cai, D. Jiang, Yanhui Yin, Cheng-Feng Qin, Jing Li, X. Gong, X. Lou, Wen Shi, Dongdong Wu, Hengming Zhang, Lang Zhu, Wei Deng, Yurong Li, Jin-Xing Lu, Changgui Li, Xiangxi Wang, W. Yin, Yanjun Zhang, Chuan Qin   +33 more
semanticscholar   +1 more source

Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile

New England Journal of Medicine, 2021
Background Mass vaccination campaigns to prevent coronavirus disease 2019 (Covid-19) are occurring in many countries; estimates of vaccine effectiveness are urgently needed to support decision making.
A. Jara, E. Undurraga, C. González, F. Paredes, Tomás Fontecilla, G. Jara, A. Pizarro, Johanna Acevedo, Katherine Leo, Francisco Leon, Carlos Sans, Paulina Leighton, P. Suárez, Heriberto E. García-Escorza, R. Araos   +14 more
semanticscholar   +1 more source

Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease

Human Vaccines & Immunotherapeutics, 2017
A therapeutic vaccine for human Chagas disease is under development by the Sabin Vaccine Institute Product Development Partnership. The aim of the vaccine is to significantly reduce the parasite burden of Trypanosoma cruzi in humans, either as a ...
Christopher A. Seid, Kathryn M. Jones, Jeroen Pollet, Brian Keegan, Elissa Hudspeth, Molly Hammond, Junfei Wei, C. Patrick McAtee, Leroy Versteeg, Amanda Gutierrez, Zhuyun Liu, Bin Zhan, Jonathan L. Respress, Ulrich Strych, Maria Elena Bottazzi, Peter J. Hotez   +15 more
doaj   +1 more source

Comprehensive Flow Cytometry Analysis of PEI-Based Transfections for Virus-Like Particle Production

Research, 2020
The generation of stable clones for biomolecule production is a common but lengthy and labor-intensive process. For complex molecules, such as viruses or virus-like particles (VLPs), the timeline becomes even more cumbersome. Thus, in the early stages of
Daniel J. Blackstock, Alvenne Goh, Shamitha Shetty, Giulia Fabozzi, Rong Yang, Vera B. Ivleva, Richard Schwartz, Joseph Horwitz   +7 more
doaj   +1 more source

Determinants of COVID-19 vaccine acceptance in the US

medRxiv, 2020
Background:The COVID-19 pandemic continues to adversely affect the U.S., which leads globally in total cases and deaths. As COVID-19 vaccines are under development, public health officials and policymakers need to create strategic vaccine-acceptance ...
A. Malik, S. McFadden, J. Elharake, S. Omer   +3 more
semanticscholar   +1 more source

Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine

New England Journal of Medicine, 2021
Background Efficacious vaccines are urgently needed to contain the ongoing coronavirus disease 2019 (Covid-19) pandemic of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
J. Sadoff, Mathieu le Gars, Georgi Shukarev, Dirk Heerwegh, C. Truyers, A. M. de Groot, Jeroen N. Stoop, Sarah M. Tete, Wim Van Damme, I. Leroux-Roels, Pieter-Jan Berghmans, Murray A. Kimmel, P. van Damme, J. de Hoon, William Smith, K. Stephenson, Stephen C. De Rosa, Kristen W. Cohen, M. McElrath, Emmanuel G. Cormier, Gert Scheper, D. Barouch, J. Hendriks, F. Struyf, M. Douoguih, J. van Hoof, H. Schuitemaker   +26 more
semanticscholar   +1 more source

COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries

Nature Medicine, 2021
Widespread acceptance of COVID-19 vaccines is crucial for achieving sufficient immunization coverage to end the global pandemic, yet few studies have investigated COVID-19 vaccination attitudes in lower-income countries, where large-scale vaccination is ...
Julio S. Solís Arce, Shana S. Warren, N. Meriggi, Alexandra Scacco, Nina McMurry, M. Voors, Georgiy Syunyaev, A. Malik, Samya Aboutajdine, Opeyemi Adeojo, Deborah Anigo, A. Armand, S. Asad, Martin Atyera, B. Augsburg, M. Awasthi, Gloria Eden Ayesiga, Antonella Bancalari, Martina Björkman Nyqvist, Ekaterina Borisova, C. M. Bosancianu, Magarita Rosa Cabra García, A. Cheema, Elliott Collins, Filippo Cuccaro, A. Farooqi, T. Fatima, M. Fracchia, Mery Len Galindo Soria, Andrea Guariso, A. Hasanain, Sofia Jaramillo, Sellu Kallon, Anthony Kamwesigye, A. Kharel, S. Kreps, Madison Levine, Rebecca Littman, M. Malik, Gisele Manirabaruta, Jean Léodomir Habarimana Mfura, Fatoma Momoh, Alberto Mucauque, Imamo Mussa, J. Nsabimana, I. Obara, María Juliana Otálora, Béchir Ouédraogo, Touba Bakary Pare, Melina R. Platas, L. Polanco, Javaeria Qureshi, M. Raheem, V. Ramakrishna, Ismail Rendr'a, T. Shah, Sarene Eyla Shaked, Jacob N. Shapiro, J. Svensson, Ahsan Tariq, Achille Mignondo Tchibozo, Hamid Ali Tiwana, Bhartendu Trivedi, Corey Vernot, Pedro C. Vicente, Laurin B. Weissinger, basit. zafar, Baobao Zhang, D. Karlan, M. Callen, Matthieu Teachout, Macartan Humphreys, A. Mobarak, S. Omer   +73 more
semanticscholar   +1 more source

Overview of vaccines and vaccination [PDF]

Molecular Biotechnology, 2005
Of the 80-plus known infectious agents pathogenic for humans, there are now more than 30 vaccines against 26 mainly viral and bacterial infections and these greatly minimize subsequent disease and prevent death after exposure to those agents. This article describes the nature of the vaccines, from live attenuated agents to subunits, their efficacy and ...
openaire   +3 more sources