Results 71 to 80 of about 1,582,509 (353)

پایداری و چرخش ارگانی ویروس تیپ o بیماری تب برفکی در خوکچه هندی [PDF]

Archives of Razi Institute, 2010
از آنجایی که خوکچه هندی به عنوان بهترین حیوان آزمایشگاهی حساس به ویروس بیماری تب برفکی مطرح شده است، مقدار یک میلی لیتر از ویروس تب برفکی تیپ O با غلظت TCID50 106-5/106به ناحیه کف پای 10 سر خوکچه هندی (سمت راست) به روش داخل پوستی تزریق شد.
محمد اسلام پناه, همایون مهروانی, محمدحسن حبل الورید, ح. ایزدی, م. ستوده, ف. جیرانی, ف. طالب لو   +6 more
doaj   +1 more source

COVID-19 vaccine acceptance among pregnant women and mothers of young children: results of a survey in 16 countries

European Journal of Epidemiology, 2021
With the development of multiple effective vaccines, reducing the global morbidity and mortality of COVID-19 will depend on the distribution and acceptance of COVID-19 vaccination.
Malia Skjefte, Michelle Ngirbabul, Oluwasefunmi Akeju, Daniel J Escudero, S. Hernández-Díaz, D. Wyszynski, J. Wu   +6 more
semanticscholar   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Occurrence of human infection with Salmonella Typhi in sub-Saharan Africa

Scientific Data
Typhoid fever, caused by Salmonella enterica serovar Typhi, results in over 1.2 million cases and 29 thousand deaths annually from sub-Saharan Africa. Combating this disease requires various intervention approaches, such as typhoid conjugate vaccines and
Jong-Hoon Kim, Prerana Parajulee, Thuy Tien Nguyen, Shreeya Wasunkar, Vittal Mogasale, Se Eun Park, Ursula Panzner, Ondari D. Mogeni, Justin Im, Florian Marks   +9 more
doaj   +1 more source

Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine

New England Journal of Medicine, 2021
Background Early clinical data from studies of the NVX-CoV2373 vaccine (Novavax), a recombinant nanoparticle vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that contains the full-length spike glycoprotein of the prototype ...
P. Heath, E. Galiza, D. Baxter, M. Boffito, D. Browne, F. Burns, D. Chadwick, R. Clark, C. Cosgrove, J. Galloway, A. Goodman, Amardeep Heer, A. Higham, Shalini Iyengar, A. Jamal, Christopher Jeanes, P. Kalra, Christina Kyriakidou, D. McAuley, Agnieszka Meyrick, A. Minassian, J. Minton, P. Moore, Imrozia Munsoor, Helen Nicholls, O. Osanlou, J. Packham, Carol H. Pretswell, Alberto San Francisco Ramos, D. Saralaya, Ray Sheridan, Richard Smith, R. Soiza, P. Swift, E. Thomson, J. Turner, M. E. Viljoen, G. Albert, I. Cho, F. Dubovsky, G. Glenn, J. Rivers, A. Robertson, Kathy Smith, S. Toback   +44 more
semanticscholar   +1 more source

Varicella Breakthrough Infection and Vaccine Effectiveness in Taiwan

, 2012
We performed this nationwide retrospective investigation among the recipients of varicella vaccine to evaluate the breakthrough varicella infection rate, factors associated with breakthrough infection and the vaccine effectiveness.
HUANG, WEN-CHAN;HUANG, LI-MIN;CHANG, I-SHOU;TSAI, FANG-YU;CHANG, LUAN-YIN, 黃文嬋;黃立民;張憶壽;蔡芳榆;張鑾英   +1 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Need, demand, and feasibility for a new iNTS vaccine: stakeholder insights from eight African countries

npj Vaccines
This study, grounded in the key stakeholders’ perspectives, highlights the critical and immediate need for the development of a new iNTS vaccine. An online survey was conducted among government officials and healthcare providers across eight African ...
Sajan Gunarathna, Yongha Hwang, Jung-Seok Lee, GeunHyeog Jang, Jean-Louis Excler, Florian Marks, Jerome H. Kim   +6 more
doaj   +1 more source

Challenges and opportunities in setting up a phase III vaccine clinical trial in resource limited settings: Experience from Nepal

Human Vaccines & Immunotherapeutics, 2021
Clinical trials are complicated, time-consuming and costly. From the initial screening, informed consent and recruitment of the participants’ to study completion, the sponsor must undertake a wide array of complex and closely monitored operations ...
Tarun Saluja, Bishnu Rath Giri, Shipra Chaudhary, Dipesh Tamrakar, Piush Kanodia, Sonali Palkar, Sridhar Vemula, Suchada Chinaworapong, Bomi Kim, Birendra Prasad Gupta, Sue Kyoung Jo, Sanet Aspinall, Ganesh Kumar Rai, Duncan Steele, Jerome H. Kim, T. Anh Wartel, Sushant Sahastrabuddhe   +16 more
doaj   +1 more source

Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Clinical Trial

Science, 2021
Description Antibody levels predict vaccine efficacy Symptomatic COVID-19 infection can be prevented by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.
P. Gilbert, D. Montefiori, A. McDermott, Y. Fong, D. Benkeser, Wei-zhi Deng, Honghong Zhou, Christopher R. Houchens, Karen Martins, L. Jayashankar, F. Castellino, B. Flach, Bob C. Lin, S. O'connell, C. McDanal, Amanda Eaton, M. Sarzotti-Kelsoe, Yiwen Lu, Chenchen Yu, B. Borate, Lars van der Laan, N. Hejazi, C. Huynh, Jacqueline Miller, Hana M. El Sahly, L. Baden, Mira Baron, Luis I. De La Cruz, C. Gay, Spyros A. Kalams, Colleen F. Kelley, M. Andrasik, James G. Kublin, L. Corey, K. Neuzil, Lindsay N. Carpp, R. Pajon, D. Follmann, R. Donis, R. Koup   +39 more
semanticscholar   +1 more source