Results 101 to 110 of about 1,015,995 (302)

Long-term cross-variant Fc-mediated immune responses against SARS-CoV-2 induced by a heterologous adenoviral/inactivated virus prime-boost vaccination strategy

npj Vaccines
Limited vaccine availability and logistical barriers during the COVID-19 pandemic have hindered homologous boosting in resource-limited regions. Therefore, heterologous prime-boost regimens have gained attention as versatile and practical alternatives ...
Doyoung Kim, Jung Hyuk Lee, Junhyeon Lee, Ju Yeon Park, Yuna Shin, Soo Ji Kim, BeomMin Cheon, Sumin Lee, Eunjin Cho, Deok Ryun Kim, Ryan P. McNamara, Cheol-Heui Yun, Mohamadou Siribie, Asma Binte Aziz, Birkneh Tilahun Tadesse, Florian Marks, Sue Kyoung Jo, Hyon Jin Jeon, Raphaël Rakotozandrindrainy, Ilesh V. Jani, Jae Seung Yang, Byoung-Shik Shim, Manki Song   +22 more
doaj   +1 more source

Costs of vaccine delivery in the Gambia before and after, pentavalent and pneumococcal conjugate vaccine introductions.

, 2014
BACKGROUND: The Gambia introduced seven-valent pneumococcal conjugate vaccine (PCV) in August 2009 and switched to 13-valent PCV in April 2011. In April 2009 monovalent hepatitis B and combined Diphtheria-Tetanus-Pertussis and Haemophilus influenzae type
Lowe-Jallow, Y, Mackenzie, G, Atherly, D, Griffiths, UK, Boye, B, Usuf, E, Suraratdecha, C   +6 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Mechanistic and antigenic boundaries of Henipavirus and Parahenipavirus glycoproteins

Nature Communications
Henipaviruses, in the Paramyxoviridae family, includes the highly virulent Nipah virus that causes reoccurring outbreaks of deadly disease. Recent discoveries of Henipavirus-like species, including the zoonotic Langya virus, have revealed much higher ...
Aaron J. May, Muralikrishna Lella, Jared Lindenberger, Alex Berkman, Ujjwal Kumar, Kejun Liu, Moumita Dutta, Maggie Barr, Rob Parks, Xiaozhi Lu, Madison Berry, Amanda Powell, Amelia G. Thompson, Sravya Sowdamini Nakka, Camila T. França, Xiao Huang, Arpita Mrigwani, Kijun Song, Victor Ilevbare, Salam Sammour, Chan Soo Park, Radha Devkota Adhikari, Priyanka Devkota, Katarzyna Janowska, Yanshun Liu, Garrett Scapellato, Taylor N. Spence, Katayoun Mansouri, Kevin Wiehe, Nancy J. Sullivan, Rosemarie Mason, Robert J. Edwards, Kevin O. Saunders, Barton F. Haynes, Priyamvada Acharya   +34 more
doaj   +1 more source

Coadministration of 13-valent pneumococcal conjugate and quadrivalent inactivated influenza vaccines in adults previously immunized with polysaccharide pneumococcal vaccine 23: a randomized clinical trial

Human Vaccines & Immunotherapeutics, 2019
Immune responses to 13-valent pneumococcal conjugate vaccine (PCV13) and quadrivalent inactivated influenza vaccine (QIV) in older adults may vary with coadministration and previous pneumococcal polysaccharide vaccination.
Allison R. Thompson, Nicola P. Klein, H. Jackson Downey, Scott Patterson, Vani Sundaraiyer, Wendy Watson, Keri Clarke, Kathrin U. Jansen, Shite Sebastian, William C. Gruber, Daniel A. Scott, Beate Schmöele-Thoma   +11 more
doaj   +1 more source

Production of EV71 vaccine candidates

, 2012
[[abstract]]Enterovirus 71 (EV71) is now recognized as an emerging neurotropic virus in Asia and with Coxsackie virus (CV) it is the other major causative agent of hand-foot-mouth diseases (HFMD).
Chong, P;Hsieh, SY;Liu, CC;Chou, AH;Yuan, CJ;Wu, SC;Liu, SJ;Chow, YH;Su, IJ;Klein, M
core   +1 more source

Immunological outcomes of new tuberculosis vaccine trials: WHO panel recommendations. [PDF]

, 2008
Willem Hanekom and colleagues make recommendations on assay harmonization for novel tuberculosis vaccine ...
Weichold Frank F, Willem A Hanekom, Uli J Fruth, T Mark Doherty, Hanekom Willem A, Doherty, T Mark, Hoft Dan F, Dan F Hoft, Shreemanta K Parida, Dockrell Hazel M, Helen Fletcher, Fruth Uli J, Hazel M Dockrell, McShane Helen, Weichold, Frank F, Frank F Weichold, Hoft, Dan F, Ottenhoff, Tom HM, Tom H M Ottenhoff, Helen McShane, Hanekom, Willem A, Fletcher Helen, Parida Shreemanta K, Fruth, Uli J, Doherty T. Mark, Parida, Shreemanta K, Dockrell, Hazel M, Fletcher, Helen, Ottenhoff Tom H. M, McShane, Helen   +29 more
core   +1 more source

Programmable Carrier‐Free All‐Enzyme Beads for Modular Continuous‐Flow Biocatalysis

Advanced Materials, EarlyView.
Genetically encoded enzyme building blocks self‐assemble into monodisperse, carrier‐free protein beads via a droplet‐based formulation strategy. These programmable catalytic particles enable modular continuous‐flow biocatalysis, from single‐enzyme reactions to multi‐enzyme cascades and bead–bead coupled reactor systems.
Jennifer Kühne, Julian S. Hertel, André Delavault, Judith Felk, Martin Peng, Lara Reuber, Felix Ott, Kim Wanner, Marc F. Münker, Adrian Neukirch, Alexei Kiselev, Kersten S. Rabe, Christof M. Niemeyer   +12 more
wiley   +1 more source

The use of a computerized database to monitor vaccine safety in Viet Nam. [PDF]

, 2005
Health information systems to monitor vaccine safety are used in industrialized countries to detect adverse medical events related to vaccinations or to prove the safety of vaccines. There are no such information systems in the developing world, but they
Ali, Mohammad, Canh, Gia Do, Park, Jin-Kyung, Minh, Tan Truong, Clemens, John D, Thiem, Dinh Vu, von Seidlein, Lorenz, Tho, Huu Le, Vaccine Safety Datalink Group, Trach, Duc Dang   +9 more
core   +2 more sources

Optimization of microcarrier cell culture process for the inactivated enterovirus type 71 vaccine development

, 2008
[[abstract]]Enterovirus 71 (EV71) is an enterovirus that could lead to severe neurological disorders and fatalities. The inactivated vaccine is an appropriate EV71 vaccine format for meeting current needs.
Wu, SC; Liu, CC; Lian, WC
core   +1 more source