Results 11 to 20 of about 2,182,415 (399)

Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape [PDF]

Nature Reviews Immunology, 2021
Where 2020 saw the development and testing of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at an unprecedented pace, the first half of 2021 has seen vaccine rollout in many countries.
John S Tregoning, Ziyin Wang, Benjamin F Pierce   +2 more
exaly   +3 more sources

BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccination Setting

New England Journal of Medicine, 2021
Background As mass vaccination campaigns against coronavirus disease 2019 (Covid-19) commence worldwide, vaccine effectiveness needs to be assessed for a range of outcomes across diverse populations in a noncontrolled setting.
N. Dagan, N. Barda, Eldad Kepten, O. Miron, Shay Perchik, M. Katz, M. Hernán, M. Lipsitch, B. Reis, R. Balicer   +9 more
semanticscholar   +1 more source

MODELO DE IMPACTO EM SAÚDE PÚBLICA DA INTRODUÇÃO DE UMA VACINA HÉRPES-ZOSTER RECOMBINANTE NO BRASIL

Brazilian Journal of Infectious Diseases, 2022
Introdução: O herpes-zoster (HZ) manifesta-se normalmente em idosos ou indivíduos imunocomprometidos a partir da reativação do vírus varicela zoster latente.
Ru Han, Thatiana Pinto, Bruna de Veras, Jesse Alves, Desiree Van Oorschot   +4 more
doaj   +1 more source

Covid-19 Vaccine Effectiveness against the Omicron (B.1.1.529) Variant

New England Journal of Medicine, 2022
Background A rapid increase in coronavirus disease 2019 (Covid-19) cases due to the omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 in highly vaccinated populations has aroused concerns about the effectiveness of current ...
N. Andrews, J. Stowe, Freja C M Kirsebom, S. Toffa, T. Rickeard, E. Gallagher, C. Gower, M. Kall, N. Groves, A. O’Connell, D. Simons, P. Blomquist, A. Zaidi, S. Nash, Nurin Iwani Binti Abdul Aziz, S. Thelwall, G. Dabrera, R. Myers, G. Amirthalingam, S. Gharbia, J. Barrett, R. Elson, S. Ladhani, N. Ferguson, M. Zambon, C. Campbell, K. Brown, S. Hopkins, M. Chand, M. Ramsay, J. Lopez Bernal   +30 more
semanticscholar   +1 more source

COVID-19 Vaccine Hesitancy Worldwide: A Concise Systematic Review of Vaccine Acceptance Rates

Vaccines, 2021
Utility of vaccine campaigns to control coronavirus 2019 disease (COVID-19) is not merely dependent on vaccine efficacy and safety. Vaccine acceptance among the general public and healthcare workers appears to have a decisive role in the successful ...
Malik Sallam
semanticscholar   +1 more source

Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19

New England Journal of Medicine, 2021
Background The Ad26.COV2.S vaccine is a recombinant, replication-incompetent human adenovirus type 26 vector encoding full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein in a prefusion-stabilized conformation.
J. Sadoff, G. Gray, A. Vandebosch, V. Cárdenas, Georgi Shukarev, B. Grinsztejn, P. Goepfert, C. Truyers, H. Fennema, B. Spiessens, K. Offergeld, Gert Scheper, K. Taylor, M. Robb, J. Treanor, D. Barouch, J. Stoddard, M. Ryser, M. Marovich, K. Neuzil, L. Corey, N. Cauwenberghs, T. Tanner, K. Hardt, Javier Ruiz-Guiñazú, Mathieu le Gars, H. Schuitemaker, J. van Hoof, F. Struyf, M. Douoguih   +29 more
semanticscholar   +1 more source

Subclass and avidity of circumsporozoite protein specific antibodies associate with protection status against malaria infection

npj Vaccines, 2021
RTS,S/AS01 is an advanced pre-erythrocytic malaria vaccine candidate with demonstrated vaccine efficacy up to 86.7% in controlled human malaria infection (CHMI) studies; however, reproducible immune correlates of protection (CoP) are elusive. To identify
Kelly E. Seaton, Rachel L. Spreng, Milite Abraha, Matthew Reichartz, Michelle Rojas, Frederick Feely, Richard H. C. Huntwork, Sheetij Dutta, Sarah V. Mudrak, S. Munir Alam, Scott Gregory, Erik Jongert, Margherita Coccia, Fernando Ulloa-Montoya, Ulrike Wille-Reece, Georgia D. Tomaras, S. Moses Dennison   +16 more
doaj   +1 more source

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

New England Journal of Medicine, 2020
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the resulting coronavirus disease 2019 (Covid-19) have afflicted tens of millions of people in a worldwide pandemic.
F. Polack, Stephen J. Thomas, N. Kitchin, J. Absalon, A. Gurtman, S. Lockhart, John L. Perez, Gonzalo Pérez Marc, E. Moreira, C. Zerbini, R. Bailey, K. Swanson, Satrajit Roychoudhury, K. Koury, Ping Li, W. Kalina, David Cooper, R. Frenck, L. Hammitt, Ö. Türeci, H. Nell, A. Schaefer, S. Ünal, D. Tresnan, Susan H. Mather, P. Dormitzer, U. Şahin, K. Jansen, W. Gruber   +28 more
semanticscholar   +1 more source

Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants.

New England Journal of Medicine, 2023
BACKGROUND Whether vaccination during pregnancy could reduce the burden of respiratory syncytial virus (RSV)-associated lower respiratory tract illness in newborns and infants is uncertain.
B. Kampmann, S. Madhi, I. Munjal, E. Simões, B. Pahud, C. Llapur, J. Baker, Gonzalo Pérez Marc, D. Radley, Emma Shittu, Julia R Glanternik, Hasra Snaggs, James Baber, Philip Zachariah, S. Barnabas, Merlin Fausett, Tyler Adam, Nicole Perreras, M. V. van Houten, A. Kantele, Li-Min Huang, Louis J. Bont, Takeo Otsuki, Sergio L Vargas, Joanna Gullam, B. Tapiéro, R. Stein, F. Polack, H. Zar, N. B. Staerke, María Duron Padilla, Peter C. Richmond, K. Koury, Katherine Schneider, E. V. Kalinina, David Cooper, K. Jansen, A. Anderson, K. Swanson, W. Gruber, A. Gurtman   +40 more
semanticscholar   +1 more source

Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine

New England Journal of Medicine, 2020
Background Vaccines are needed to prevent coronavirus disease 2019 (Covid-19) and to protect persons who are at high risk for complications. The mRNA-1273 vaccine is a lipid nanoparticle–encapsulated mRNA-based vaccine that encodes the prefusion ...
L. Baden, Hana M. El Sahly, B. Essink, K. Kotloff, S. Frey, R. Novak, D. Diemert, S. Spector, N. Rouphael, C. Creech, J. Mcgettigan, Shishir Kehtan, N. Segall, Joel Solis, A. Brosz, C. Fierro, H. Schwartz, K. Neuzil, L. Corey, P. Gilbert, H. Janes, D. Follmann, M. Marovich, J. Mascola, L. Polakowski, J. Ledgerwood, B. Graham, H. Bennett, R. Pajon, C. Knightly, B. Leav, W. Deng, Honghong Zhou, Shu Han, M. Ivarsson, Jacqueline M. Miller, T. Zaks   +36 more
semanticscholar   +1 more source