Results 251 to 260 of about 886,403 (306)
Advanced Science, EarlyView.This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo +10 more
wiley +1 more source
XXXVIII. First Report on Investigations into Plague Vaccines [PDF]
, 1910 Sydney Rowland
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Advanced Science, EarlyView.The ssLAMP method amplifies the nucleic acid of pathogen and identifies SNP mutations. By combining the portable detection device with smartphone‐based analysis software, enables rapid, on‐site SNP detection and genotyping of SARS‐Cov‐2 Omicron variants, providing a cost‐effective and field‐deployable solution for precise pathogen identification in ...
Qijie Lin +19 more
wiley +1 more source
Some Observations ON THE BACTERIOLOGY AND VACCINE TREATMENT OF CHRONIC BRONCHITIS: Based on 300 Cases, with Special Reference to Associated Nasal Infections [PDF]
, 1922 L. Mackey
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Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine
Advanced Science, EarlyView.A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li +14 more
wiley +1 more source
Studies on Chick Embryo Vaccines Against Japanese B Encephalitis [PDF]
, 1946 Hilary Koprowski, Herald R. Cox
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Advanced Science, EarlyView.A new strategy of “confined eutectic” is proposed to achieve fluorochromic materials that can readout refrigeration temperature with naked‐eye. It leverages changes in the crystallinity of the confined eutectics in nano/micro‐domains to regulate the aggregation and dispersion states of fluorophores.
Jifang Zhao +4 more
wiley +1 more source
Serum and Vaccine Therapy in Combination with Sulphanilamide or M and B 693 [PDF]
, 1939 Alexander Fleming
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Advanced Electronic Materials, EarlyView.The single‐molecule with a large transistor‐SiMoT is proposed for the detection of the subgenomic RNA of SARS‐CoV‐2, achieving a diagnostic sensitivity of 98.0% and a specificity of 87.8%. The SiMoT technology, currently at TRL‐5, is suitable for point‐of‐care settings and delivers the result to the end user in 30 min.
Eleonora Macchia +12 more
wiley +1 more source