Results 271 to 280 of about 886,403 (306)
This is the second installment in the series, “The Interview with the World‐Class Authorities.” We are honored to welcome Prof. Luis Diaz, the Director of the Division of Solid Tumor Oncology at Memorial Sloan Kettering Cancer Center and Editor‐in‐Chief of Cancer Discovery. Prof.
Haruna Takeda+4 more
wiley +1 more source
Role of radiotherapy in surgical approaches to pancreatic cancer treatment: A narrative review
This review explores the role of radiotherapy (RT) in the multidisciplinary treatment of pancreatic ductal adenocarcinoma (PDAC), focusing on its integration with surgical strategies to improve resectability, local control, and survival outcomes while addressing potential challenges and future research directions.
Satoshi Yasuda+4 more
wiley +1 more source
An anti‐inflammatory and antioxidant metal‐organic framework (MOF) nanoplatform was prepared via one‐pot self‐assembly. In vitro and in vivo studies demonstrated that the prepared MVPC nanoparticles can effectively scavenge overproduced reactive oxygen species at diseased sites, enhance IL‐10 secretion, and suppress VEGFA expression, offering a novel ...
Shundong Cai+12 more
wiley +1 more source
The study investigates lipopeptides as alternatives to classical antibiotics, focusing on a palmitoylated tetrapeptide that shows potent antibacterial activity but poses toxicological challenges. The formation of host–guest inclusion complexes with cyclodextrins mitigates lipopeptide toxicity and enhances solubility while preserving efficacy, providing
Chiara Bellini+9 more
wiley +1 more source
Abstract The effect of shear stress on cell behaviors should be considered for designing the suspension culture of mammalian cells. Computational flow dynamics (CFD) is a promising tool for estimating shear stress on cells, but the accuracy is limited due to resolution limitations.
Ikki Horiguchi+2 more
wiley +1 more source
Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives
ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley +1 more source