Results 21 to 30 of about 1,325,849 (308)

Immunotherapeutic Potential of CpG Oligonucleotides in Chickens

open access: yesThe Journal of Poultry Science, 2009
Synthetic oligodeoxynucleotides (ODN) containing CpG motifs activate innate and adaptive immune responses in numerous vertebrate species. The protective effects of CpG ODN against viral, bacterial and protozoal pathogens have been well documented in ...
Arshud Dar   +4 more
doaj   +1 more source

SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice

open access: yesHuman Vaccines & Immunotherapeutics, 2021
There is an urgent need for an accessible and low-cost COVID-19 vaccine suitable for low- and middle-income countries. Here, we report on the development of a SARS-CoV-2 receptor-binding domain (RBD) protein, expressed at high levels in yeast (Pichia ...
Jeroen Pollet   +19 more
doaj   +1 more source

Safety and immunogenicity of a reformulated Vietnamese bivalent killed, whole-cell, oral cholera vaccine in adults.

open access: yes, 2007
Vietnam currently produces an orally administered, bivalent (O1 and O139) killed whole-cell vaccine and is the only country in the world with endemic cholera to use an oral cholera vaccine in public health practice.
Anh, Dang Duc   +13 more
core   +1 more source

Recombinant MVA-prime elicits neutralizing antibody responses by inducing antigen-specific B cells in the germinal center

open access: yesnpj Vaccines, 2021
The RV144 HIV-1 vaccine trial has been the only clinical trial to date that has shown any degree of efficacy and associated with the presence of vaccine-elicited HIV-1 envelope-specific binding antibody and CD4+ T-cell responses.
Leila Eslamizar   +23 more
doaj   +1 more source

Randomized, Controlled Trial of the Long Term Safety, Immunogenicity and Efficacy of RTS,S/AS02(D) Malaria Vaccine in Infants Living in a Malaria-Endemic Region. [PDF]

open access: yes, 2013
The RTS,S/AS malaria candidate vaccine is being developed with the intent to be delivered, if approved, through the Expanded Programme on Immunization (EPI) of the World Health Organization.
A Olotu   +43 more
core   +5 more sources

Meningococcal serogroup B vaccines: Estimating breadth of coverage

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Neisseria meningitidis serogroup B (MenB) is an important cause of invasive meningococcal disease. The development of safe and effective vaccines with activity across the diversity of MenB strains has been challenging.
Robert G. K. Donald   +9 more
doaj   +1 more source

پایداری و چرخش ارگانی ویروس تیپ o بیماری تب برفکی در خوکچه هندی [PDF]

open access: yesArchives of Razi Institute, 2010
از آنجایی که خوکچه هندی به عنوان بهترین حیوان آزمایشگاهی حساس به ویروس بیماری تب برفکی مطرح شده است، مقدار یک میلی لیتر از ویروس تب برفکی تیپ O با غلظت TCID50 106-5/106به ناحیه کف پای 10 سر خوکچه هندی (سمت راست) به روش داخل پوستی تزریق شد.
محمد اسلام پناه   +6 more
doaj   +1 more source

Challenges and opportunities in setting up a phase III vaccine clinical trial in resource limited settings: Experience from Nepal

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Clinical trials are complicated, time-consuming and costly. From the initial screening, informed consent and recruitment of the participants’ to study completion, the sponsor must undertake a wide array of complex and closely monitored operations ...
Tarun Saluja   +16 more
doaj   +1 more source

Epidemiology of Any and Vaccine-Type Anogenital Human Papillomavirus Among 13-26-Year-Old Young Men After HPV Vaccine Introduction [PDF]

open access: yes, 2018
PURPOSE: The aims of this study were to determine prevalence of and factors associated with any human papillomavirus (HPV) and vaccine-type HPV among young men after vaccine introduction, stratified by vaccination status.
Bernstein, David I.   +7 more
core   +1 more source

Conducting a phase III clinical trial in children during the COVID- 19 pandemic: Experience and lessons learnt from a clinical research facility of Nepal

open access: yesHuman Vaccines & Immunotherapeutics, 2023
Clinical trials in humans are vital to test safety and efficacy of new interventions and are accompanied with the complexity of related regulatory guidelines, stringent time frame and financial burden particularly when participants are children ...
Ram Hari Chapagain   +19 more
doaj   +1 more source

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