Results 291 to 300 of about 2,182,415 (399)

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, EarlyView.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

Comparative immunoinformatic analysis of Rhipicephalus microplus cocktail vaccine targets. [PDF]

Parasit Vectors
Hendawy SHM, Alzan HF, Ueti MW.
europepmc   +1 more source

Edible Pneumatic Battery for Sustained and Repeated Robot Actuation

Advanced Science, EarlyView.
This work presents an edible energy source and valve system to power soft, pneumatically driven edible robots. A chemical reaction between sodium bicarbonate and citric acid generates carbon dioxide gas, and a pressure‐triggered edible valve enables self‐repetitive motion of the edible actuator.
Bokeon Kwak, Shuhang Zhang, Alexander Keller, Qiukai Qi, Jonathan Rossiter, Dario Floreano   +5 more
wiley   +1 more source

Exploring COVID-19 vaccine attitudes among pregnant women: key factors and strategies to enhance uptake. [PDF]

NPJ Womens Health
Parish MA, Badhwar S, Tan HL, Causbhoy I, Kretz A, Sheffield J, Klein SL, Morgan R.   +7 more
europepmc   +1 more source

Evaluation of reproductive protection against bovine viral diarrhea virus and bovine herpesvirus-1 afforded by annual revaccination with modified-live viral or combination modified-live/killed viral vaccines after primary vaccination with modified-live viral vaccine

, 2017
Paul H. Walz, M. Daniel Givens, Soren P. Rodning, K.P. Riddell, Bruce W. Brodersen, Daniel W. Scruggs, Timothy G. Short, Dale M. Grotelueschen   +7 more
openalex   +1 more source

Low-fidelity Venezuelan equine encephalitis virus polymerase mutants to improve live-attenuated vaccine safety and efficacy [PDF]

, 2018
Tiffany F. Kautz, Mathilde Guerbois, Kamil Khanipov, Edward I. Patterson, Rose M. Langsjoen, Ruimei Yun, Kelsey Lane Warmbrod, Yuriy Fofanov, Scott C. Weaver, Naomi L. Forrester   +9 more
openalex   +1 more source

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, EarlyView.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source

Risk of autoimmune disease flares after recombinant zoster vaccine: A vaccine safety analysis based on the Vaccine Adverse Event Reporting System database. [PDF]

Hum Vaccin Immunother
Liu G, Zhang X, Wang Y, Wang Y, He P, Yu Q.   +5 more
europepmc   +1 more source

Measles outbreaks and public attitudes towards vaccine exemptions: some cautions and strategies for addressing vaccine hesitancy [PDF]

, 2019
Sandra Crouse Quinn, Amelia Jamison, Vicki S. Freimuth   +2 more
openalex   +1 more source

Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV

Advanced Science, EarlyView.
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao, Xu‐Ying Pei, Yuan‐Yuan Zhang, Juan Xie, Jing‐Wei Tu, Zhuo‐Jun Liu, Yi‐Yang Ding, Chen‐Hua Yan, Yu‐Hong Chen, Yu Wang, Lan‐Ping Xu, Xiao‐Hui Zhang, Xiao‐Jun Huang, Xiang‐Yu Zhao   +13 more
wiley   +1 more source