Results 21 to 30 of about 389,573 (268)
Immunogenicity of inactivated rotavirus in rhesus monkey, and assessment of immunologic mechanisms
Human Vaccines & Immunotherapeutics, 2023 Rotavirus is one of the main pathogens causing severe diarrhea in infants and young children < 5 years of age. The development of the next-generation rotavirus vaccine is of great significance for preventing rotavirus infection and reducing severe ...
Yan Zhou +16 more
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Human Vaccines & Immunotherapeutics, 2019 Immune responses to 13-valent pneumococcal conjugate vaccine (PCV13) and quadrivalent inactivated influenza vaccine (QIV) in older adults may vary with coadministration and previous pneumococcal polysaccharide vaccination.
Allison R. Thompson +11 more
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Development of a Zika vaccine [PDF]
Expert Review of Vaccines, 2016 Currently, there is no approved vaccine against the Zika virus (ZIKV). However, several organizations are actively developing vaccines using various platforms and technologies.
Ralph A, Tripp, Ted M, Ross
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Expert Review of Vaccines, 2018 Introduction; Adults, particularly those with underlying chronic conditions, eg, cardiovascular, liver, and pulmonary diseases and diabetes mellitus, have a persistent pneumococcal disease burden. Thirteen-valent pneumococcal conjugate vaccine (PCV13) is
Raul E. Isturiz +7 more
doaj +1 more source
The Lancet, 2004 Large gains in the reduction of malaria mortality in the early 20th century were lost in subsequent decades. Malaria now kills 2-3 million people yearly. Implementation of malaria control technologies such as insecticide-treated bednets and chemotherapy could reduce mortality substantially, but an effective malaria vaccine is also needed.
Moorthy, V, Good, M, Hill, A
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Development of antistaphylococcal vaccines [PDF]
Current Infectious Disease Reports, 2001 Staphylococcus aureus is frequently isolated from both hospital-acquired and community-acquired infections, and the emergence of antibiotic resistance among clinical isolates has made treatment of staphylococcal infections difficult. This scenario has sparked renewed interest in the development of a vaccine for individuals at high risk for ...
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The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
Covering all the bases: Preclinical development of an effective Staphylococcus aureus vaccine
Frontiers in Immunology, 2014 A key aspect of the pathogenesis of the Gram positive bacterium Staphylococcus aureus is its ability to rapidly adapt to the host environment during the course of an infection.
Ingrid L Scully +3 more
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Development of a malaria vaccine
The Lancet, 1997 Development of an effective malaria vaccine poses a major scientific challenge both in the laboratory and in the field. Such a vaccine is necessary because of the massive disease burden of malaria in the developing world, the global spread of drug resistance, and the difficulty of sustainable control of the mosquito vector. Animal models have shown the
Kwiatkowski, D, Marsh, K
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source