Results 171 to 180 of about 165,324 (266)

A Multidesign Study of 4CMenB Vaccine Effectiveness and Impact on Meningococcal Carriage and Gonorrhea in Northern Territory Adolescents and Young People. [PDF]

Open Forum Infect Dis
McMillan M, Wang B, Krause V, Greenwood-Smith B, Webby R, Chen J, Baird R, Gerrell J, Prince K, Whop L, Giles L, Bednarz J, Kaldor J, D'Antoine H, Binks M, Andrews R, Richmond P, Macartney K, Whiley D, Lawrence A, Petousis-Harris H, Ward J, Marshall H.   +22 more
europepmc   +1 more source

Detaching Photosensitive Nanoparticles from Cells Prevents Them from Remaining in Cells after Photoporation

Advanced Science, EarlyView.
Phenylboronic acid‐functionalized gold nanoparticles reversibly attach to cell‐surface glycans, enhancing photoporation‐mediated intracellular delivery. After irradiation, ATP competitively disrupts the boronic ester interactions and removes cell‐associated nanoparticles, markedly reducing residual gold.
Tao Lu, Mina Nikolić, Baihao Huang, Deep Punj, Herlinde De Keersmaecker, Thibaut Van Acker, Wenjia Xie, Florian Vanlauwe, Phillip Blondeel, Liesl De Graeve, Félix Sauvage, Ranhua Xiong, Chaobo Huang, Frank Vanhaecke, Kevin Braeckmans, Stefaan C. De Smedt   +15 more
wiley   +1 more source

Maternal RSVpreF Vaccine Effectiveness Against Respiratory Syncytial Virus in Hospitalized Infants.

JAMA Pediatr
Wadia U, Ong MM, Cox SN, Le H, Foo D, Wolf Mankiewicz S, Carr J, Marshall HS, Clark JE, Britton PN, McMullan B, Tan Y, Wiid Z, Tosif S, Hung TY, Moore HC, Hayford K, Cané A, Fell DB, Atwell JE, Richmond PC, STREETON Study Working Group.   +21 more
europepmc   +1 more source

Influenza A(H3N2) Subclade K: Epidemiology, Molecular Evolution and Vaccine Effectiveness in Europe. [PDF]

Pathogens
Scarvaglieri I, De Francesco MA, Alberti M, Cesanelli F, Salvi M, Tiecco G, Castelli F, Quiros-Roldan E.   +7 more
europepmc   +1 more source

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

Advanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei, Tanja Groll, Stephanie Kahl, Silke Baer, Elisabeth Bliemsrieder, Frits H. A. van Heijster, Andre Wendlinger, Pascal Wodtke, Jorge Cabello, Susan Notohamiprodjo, Christian Lohrmann, Markus Schwaiger, Wolfgang A. Weber, Katja Steiger, Andrea Meyer‐Lindenberg, Johannes Hirschberger, Christine Baumgartner, Franz Schilling   +17 more
wiley   +1 more source

Intraseasonal waning of influenza vaccine effectiveness and implications for the optimal timing of seasonal vaccination programs: A scoping review. [PDF]

Can Commun Dis Rep
Doyon-Plourde P, Tadount F, Gil A, Lazarescu C, Ursu MM, Sicard N, Siu W, Sinilaité A.   +7 more
europepmc   +1 more source

NS1‐Induced PARP1 Phase Transitions Prolongs Host Transcriptional Pausing to Promote Influenza A Virus Replication

Advanced Science, EarlyView.
After IAV infection, NS1 induces PARP1 phase transition, reducing molecular mobility in condensates, prolonging host transcriptional pause, aiding RdRp cap snatching, and promoting viral transcription. ABSTRACT Influenza A virus (IAV) commandeers host transcriptional machinery to replicate, but mechanisms remain elusive.
Shufeng Ma, Changyuan Kang, Xixian Liu, Lichao Yang, Mengyi Li, Yuting Ye, Jianfang Zhang, Yingjun Li, Guanghui Jin, Yang Liu, Xiaohong Chen, Kexin Wang, Zifeng Yang   +12 more
wiley   +1 more source

Primary Care-Based Estimates of Influenza Vaccine Effectiveness in Hungary, 2024/25. [PDF]

Vaccines (Basel)
Túri G, Velkey V, Juhász KM, Krisztalovics K, Ferenczi A, Luca C, Bilics E, Kristóf K, Oroszi B.   +8 more
europepmc   +1 more source

TROP2‐Targeting Chimeras (TRTACs) for Tumor Cell‐Selective Membrane Protein Degradation and Enhanced Drug Delivery

Advanced Science, EarlyView.
TROP2 is identified as a novel tumor‐selective lysosomal‐targeting receptor with established clinical relevance. TROP2‐targeting chimeras (TRTACs) are developed by genetically fusing a TROP2‐binding nanobody to nanobodies against specific target proteins.
Luping Chen, Xinying Fu, Wenqian Dong, Xiaobei Deng, Simin Chen, Fujun Wang, Jian Zhao, Shiqun Shao, Liqiang Fan, Jingyu Zhang, Lixin Zhang   +10 more
wiley   +1 more source

Analysis of epidemiological characteristics and vaccine effectiveness of pertussis in Linping District, China. [PDF]

Front Public Health
Liu T, Chen Q, Ye C, Shen J, Zhu C, Yang P, Han R, Zhang C.   +7 more
europepmc   +1 more source