Results 171 to 180 of about 8,480 (214)
Advanced NanoBiomed Research, EarlyView.Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi +6 more
wiley +1 more source
Safety and Feasibility of Magnetic Separation‐Based Blood Purification
Advanced NanoBiomed Research, EarlyView.We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora +11 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley +1 more source
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Nonspecific Effects of Vaccines
JAMA, 2014Vaccination is one of the great public health achievements of the last 100 years.1 The development of vaccination has led to the eradication of smallpox, the reduction of the worldwide incidence of polio by 99%, and the control of measles, with a 74% decline in global measles deaths since 2000.2 With the decline in vaccine-preventable diseases that ...
David, Goldblatt, Elizabeth, Miller
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Vaccine, 2016
The heterologous or non-specific effects (NSEs) of vaccines, at times defined as "off-target effects" suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important ...
Mitra Saadatian-Elahi +8 more
openaire +3 more sources
The heterologous or non-specific effects (NSEs) of vaccines, at times defined as "off-target effects" suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important ...
Mitra Saadatian-Elahi +8 more
openaire +3 more sources
Distinguishing vaccine efficacy and effectiveness [PDF]
Vaccine, 2012 Mathematical models of disease transmission and vaccination typically assume that protective vaccine efficacy (i.e. the relative reduction in the transmission rate among vaccinated individuals) is equivalent to direct effectiveness of vaccine. This assumption has not been evaluated.We used dynamic epidemiological models of influenza and measles ...
Alison Galvani, Eunha Shim
exaly +3 more sources
On Measures and Models for the Effectiveness of Vaccines and Vaccination Programmes
International Journal of Epidemiology, 1988Smith, Rodrigues and Fine have discussed and linked different measures, models, and study designs for the assessment of vaccines. The present paper responds to a number of issues implicitly raised by these authors. In particular, it is argued that measures and models need to be considered independently, with choice of measure depending on evaluation ...
S, Greenland, R R, Frerichs
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Genetic Effects on Vaccination
1999This chapter discusses genetic effects on vaccination. Genetic control of disease resistance is polygenic and involves quantitative trait loci (QTL), which are additive and dictate the genetic component of variation in individual resistance to infectious disease.
B N, Wilkie, B A, Mallard
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Mathematical Biosciences, 1991
A population with (individually) varying susceptibilities to infection and a vaccine with (individually) varying protective effect are considered. A simple stochastic model is used to illustrate different effects of the vaccine on the spread of the infection.
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A population with (individually) varying susceptibilities to infection and a vaccine with (individually) varying protective effect are considered. A simple stochastic model is used to illustrate different effects of the vaccine on the spread of the infection.
openaire +2 more sources
Nutritional Effects on Vaccination
1999Immune-induced cachetic response is an example of a biological opportunity to develop technologies that ensure improved performance in animal agriculture. We have estimated that reduced performance of immune stimulated animals, whether by exposure to conventional environments or through vaccination, results in more than U.S.
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