Results 191 to 200 of about 330,204 (355)

Assessing Residual Bias in Estimating Influenza Vaccine Effectiveness

, 2018
Anne M. Butler, J. Bradley Layton, Whitney S. Krueger, Abhijit V. Kshirsagar, Leah J. McGrath   +4 more
openalex   +2 more sources

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Rabies Post Exposure Vaccine Effectiveness: A Retrospective Case-Control Study in Amhara Region, Ethiopia. [PDF]

Scientifica (Cairo)
Bahiru A, Mekonnen SA, Yizengaw L, Kenubih A, Aklog W, Walle Y, Chane GM, Tibebu A, Yitbarek T, Jemberu WT, Molla W.   +10 more
europepmc   +1 more source

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

Advanced Science, EarlyView.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su, Meng Yang, Xinfeng Wang, Pa Wu, Zongzhao Zhai   +4 more
wiley   +1 more source

Intraseasonal Waning of Influenza Vaccine Effectiveness and Optimal Timing for Seasonal Influenza Vaccination Programs - Scoping Review Protocol

Fazia Tadount, Sinilaite, Angela
openalex   +1 more source

Interim estimates of 2013/14 vaccine effectiveness against influenza A(H1N1)pdm09 from Canada’s sentinel surveillance network, January 2014 [PDF]

, 2014
Danuta M. Skowronski, Catharine Chambers, Suzana Sabaiduc, Gaston De Serres, James A. Dickinson, A.-L. Winter, K Fonseca, Jonathan B. Gubbay, Hugues Charest, M Petrić, Mel Krajden, Salaheddin M. Mahmud, Paul Van Caeseele, Trijntje L. Kwindt, Alireza Eshaghi, Nathalie Bastien, Y Li   +16 more
openalex   +1 more source

Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy

Advanced Science, EarlyView.
A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao, Shan Qiao, Jie Bai, Jingjing Zhang, Zhiqin Xi, Zhenzhen Li, Xuelin Zhan, Ying Zhang, Xiaotong Yu, Yao Chen, Yijin Liu   +10 more
wiley   +1 more source

COVID-19 Vaccine Effectiveness in Patients With Hematologic Malignancies: A Nationwide Cohort Study. [PDF]

J Infect Dis
Hofsink Q, Lissenberg-Witte BI, Haggenburg S, Goorhuis A, Hazenberg MD, Rutten CE, den Tex P, de Vries EGE, van der Veldt AAM, Kemmeren JM, de Keizer NF, Huijgens PC, Dinmohamed AG, van Roon A, Pijpers J, van Roekel C, van den Hof S, Hahné SJM, de Gier B, Heijmans J, Nijhof IS.   +20 more
europepmc   +1 more source

Localized NF‐κB Inhibition Reduces Lipid Nanoparticle‐Associated Inflammation

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) activate NF‐κB and provoke inflammation that limits therapeutic delivery. By encapsulating selective NF‐κB inhibitors within LNPs, localized suppression of inflammatory signaling is achieved without compromising mRNA expression.
Carolann L. Espy, Jichuan Wu, Serena Omo‐Lamai, Liuqian Wang, Fengyi Dong, Aleksa Milosavljevic, Sarah O'Neill, Taylor Brysgel, Yufei Wang, Michael Zaleski, Emily Wolfe, Rhea Maheshwari, Manthan Patel, Dirk Trauner, Jia Nong, Zhicheng Wang, Jacob S. Brenner   +16 more
wiley   +1 more source

Mumps Virus: Replication, Immune Response, and the Changing Landscape of Vaccine Effectiveness. [PDF]

Pathogens
Risalvato J.
europepmc   +1 more source