Results 51 to 60 of about 165,324 (266)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Early and Late Influenza Vaccine Effectiveness in South Korea During the 2023–2024 Season

Vaccines
Background: During the 2023–2024 season, the influenza epidemic in South Korea peaked earlier, and the influenza vaccination rate among individuals aged ≥ 65 was high (82.2%).
Yu Jung Choi, Joon Young Song, Seong-Heon Wie, Jacob Lee, Jin-Soo Lee, Hye Won Jeong, Joong Sik Eom, Jang Wook Sohn, Won Suk Choi, Eliel Nham, Jin Gu Yoon, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim   +13 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Interim Vaccine Effectiveness Against Influenza and Hospitalization, Republic of Korea, 2024–2025 (HIMM Network)

Vaccines
Background: Influenza cases have surged earlier than usual during the 2024–2025 season, with A/H1N1 (pdm09) being the dominant strain. We aimed to investigate early estimates of influenza vaccine effectiveness (VE) for the 2024–2025 season to enhance our
Yu Jung Choi, Joon Young Song, Seong-Heon Wie, Jacob Lee, Jin-Soo Lee, Hye Won Jeong, Joong Sik Eom, Jang Wook Sohn, Won Suk Choi, Eliel Nham, Jin Gu Yoon, Ji Yun Noh, Hee Jin Cheong   +12 more
doaj   +1 more source

Varicella vaccine dose depended effectiveness and waning among preschool children in Hong Kong

Human Vaccines & Immunotherapeutics, 2020
In Hong Kong, universal varicella vaccination was introduced in July 2014 with a two-dose schedule but the vaccines had been available in the private market since 1996.
Yung-Wai Desmond Chan, W John Edmunds, Hong-Lam Chan, Miu-Ling Wong, Ka-Wing Albert Au, Shuk-Kwan Chuang, Albert Jan van Hoek, Stefan Flasche   +7 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A global living systematic review and meta-analysis hub of emerging vaccines in pregnancy and childhood

Reproductive Health
The COVID-19 pandemic accelerated vaccine development and generated a rapidly evolving body of evidence before and after the vaccine rollout. We developed a robust online platform to efficiently synthesize this emerging information for current and future
Agustín Ciapponi, Ariel Bardach, Mabel Berrueta, Jamile Ballivian, Martin Brizuela, Julieta Caravario, Noelia Castellana, Daniel Comande, Esteban Couto, Agustina Mazzoni, Vanesa Ortega, Edward P. K. Parker, Juan M. Sambade, Salva Florencia, Juan Pablo Smutny, Katharina Stegelmann, Xu Xiong, Andy Stergachis, Flor M. Munoz, Pierre Buekens   +19 more
doaj   +1 more source

Effectiveness of the influenza vaccine for preventing laboratory-confirmed influenza infections in outpatient immunocompromised adults, 2017–2018

Human Vaccines & Immunotherapeutics
While the number of immunocompromised (IC) individuals continues to rise, the existing literature on influenza vaccine effectiveness (VE) in IC populations is limited.
Kailey Hughes Kramer, Richard K. Zimmerman, Catherine L. Haggerty, G. K. Balasubramani, Mary Patricia Nowalk, Emily T. Martin, Manjusha Gaglani, C. Hallie Phillips, Edward Belongia, Jessie Chung, Fernanda P. Silveira   +10 more
doaj   +1 more source

Vaccine epidemiology, evaluation, and constraints of vaccine effectiveness -A review

Veterinary Vaccine, 2022
Vaccines are all biological substances produced from living things, administered to trigger the host's body defense system to develop immunity against a specific pathogen from which they are produced.
Habtamu Endale, Saliman Aliye, Mesfin Mathewos   +2 more
doaj   +1 more source

Effectiveness Of The Pigeon Pox Vaccine On The Chicken Vaccinated With Avian Influenza Vaccine [PDF]

Journal of Applied Veterinary Sciences, 2019
Evaluation of the effectiveness of pigeon pox (PP) vaccine in improvement the required immunity to avian influenza (AI) virus vaccine in birds and reducing its shedding after challenge was the object of this study.Specific pathogen free chicks were vaccinated with PP and AI in 10 groups at 5 and/or 8 days of age and/or boosted after 35 days then ...
Christine A. Mikhael, Nada, A. Fathy
openaire   +1 more source