Results 51 to 60 of about 255,990 (266)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Role of HTLV-1 orf-I encoded proteins in viral transmission and persistence

Retrovirology, 2019
The human T cell leukemia virus type 1 (HTVL-1), first reported in 1980 by Robert Gallo’s group, is the etiologic agent of both cancer and inflammatory diseases.
Sarkis Sarkis, Veronica Galli, Ramona Moles, David Yurick, Georges Khoury, Damian F. J. Purcell, Genoveffa Franchini, Cynthia A. Pise-Masison   +7 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Systems serology analysis shows IgG1 and IgG3 memory responses six years after one dose of quadrivalent HPV vaccine

Nature Communications
The WHO has given a permissive recommendation for an off-label one-dose human papillomavirus (HPV) vaccine schedule to prevent cervical cancer, based on evidence of comparable protection to two or three doses of vaccine. While neutralizing antibodies are
Chau Quang, Jeremy Anderson, Fiona M. Russell, Rita Reyburn, Tupou Ratu, Evelyn Tuivaga, Rachel Devi, Ian H. Frazer, Suzanne M. Garland, Bruce Wines, P. Mark Hogarth, Kim Mulholland, Amy W. Chung, Zheng Quan Toh, Paul V. Licciardi   +14 more
doaj   +1 more source

Evaluation of anti-tetanus IgG antibody levels and influencing factors in patients undergoing hemodialysis

Frontiers in Immunology
AimThis study aimed to assess anti-tetanus IgG antibody levels and identify determinants of inadequate tetanus immunity among maintenance hemodialysis (HD) patients.MethodsIn this cross-sectional study, anti-tetanus IgG levels were measured by ...
Metin Özsoy, Hakkı Öztürk, Ayşegül Tuna, Artuner Varlıbaş, Salih Cesur, Altan Aksoy, Aydın Çifci, Mehmet Emin Demir   +7 more
doaj   +1 more source

Solid‐State Nanopore Characterization of Dendrimer‐Peptide Conjugates Across Defined Peptide Loadings

Advanced Materials Interfaces, EarlyView.
Solid‐state nanopores are used to interrogate dendrimer‐peptide conjugates with systematically varied peptide loading. Single‐particle ionic current signatures reveal how ligand density modulates deformability, transport pathways, and electromechanical coupling during translocation.
Chaoming Gu, Jin Woong Lee, Kamruzzaman Joty, Marisela Leon, Santosh Khatri, Janeesha Manawasinghe, Seungpyo Hong, Min Jun Kim   +7 more
wiley   +1 more source

Proteomic and serologic assessments of responses to mRNA-1273 and BNT162b2 vaccines in human recipient sera

Frontiers in Immunology
IntroductionThe first vaccines approved against SARS-CoV-2, mRNA-1273 and BNT162b2, utilized mRNA platforms. However, little is known about the proteomic markers and pathways associated with host immune responses to mRNA vaccination.
Thomas E. Hickey, Uma Mudunuri, Heidi A. Hempel, Troy J. Kemp, Nancy V. Roche, Keyur Talsania, Brian A. Sellers, James M. Cherry, Ligia A. Pinto   +8 more
doaj   +1 more source

Study of vaccination and vaccine immunity

Kazan medical journal, 1935
In a previous work, the authors showed that vaccination and revaccination phenomena of a person depend to a large extent on the living conditions in which the vaccinated person is located, on his age and sex. Since these data were obtained on statistical material and, therefore, may meet with completely legitimate objections, the authors checked their ...
A. Groth, H. Münsterer
openaire   +1 more source

CPP–PEG‐Guided Surface Engineering of Mitochondria Enables Efficient Cellular Uptake and Respiratory Modulation

Advanced Materials Interfaces, EarlyView.
PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi, Yukari Muramatsu, Akihiro Nakaya, Yuji Maruo, Rick C. Tsai, Masashi Suganuma, Hisashi Ohta, Atsuhito Takeda, Hideyoshi Harashima, Yuma Yamada   +9 more
wiley   +1 more source

Microneedles Mediated Delivery of Nanodiamonds for Quantum Sensing of Free Radicals in Skin Tissue

Advanced Materials Technologies, EarlyView.
Fluorescent nanodiamonds are nanoscale sensors capable of monitoring cellular stress responses. However, to function effectively, they must be delivered into cells or tissues. Here, we demonstrate their application in the skin by developing a dissolvable microneedle platform that dissolves after skin insertion, enabling the delivery of nanodiamonds ...
Siyu Fan, Maria Carmona Lobita, Thea Vedelaar, Yue Zhang, Claudia Reyes‐San‐Martin, Tomás Bauleth‐Ramos, Gésinda Geertsema‐Doornbusch, Han Gao, Mohammad‐Ali Shahbazi, Hélder A. Santos, Romana Schirhagl   +10 more
wiley   +1 more source