Results 191 to 200 of about 2,769,024 (292)

Utilization of immune checkpoint inhibitors for the treatment of cancer in Scotland, 2018–2024: A national retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of the study is to describe the use of immune checkpoint inhibitors (ICIs) for the treatment of cancer in Scotland. Methods The retrospective observational cohort study included patients aged 18 years or older who commenced treatment with an ICI in Scotland between 1 January 2018 and 31 December 2024.
Tanja Mueller, Christine Crearie, Liya Lu, Jiafeng Pan, Fraser N. Sneden, David Martin, Amanj Kurdi, Catherine S. Thomson, Julie Clarke, Marion Bennie   +9 more
wiley   +1 more source

Bivalent RSVpreF Subunit Vaccine Safety and Immunogenicity in Seropositive 2-<18 Year Olds. [PDF]

Vaccines (Basel)
Glanternik J, Paulsen GC, Senders S, Smith M, Shittu E, Pahud BA, Pereira L, Chen L, Maddalena Lino M, Kalinina EV, Baranova D, Kalina WV, Needle E, Murillo M, Leech JM, Cooper D, Swanson KA, Anderson AS, Gurtman A, Munjal I.   +19 more
europepmc   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Harmonizing Case Validation for Vaccine Safety in Real-World Data: The VAC4EU Experience. [PDF]

Clin Epidemiol
Dehghan Tarazjani A, Weibel D, Aurelius T, Zwiers LC, Van den Berg JM, Pérez-Breva L, Gimeno-Miguel A, Stona L, Solórzano M, Desalegn AA, Poblador-Plou B, Lysen TS, Wheler J, Zidan M, Carreras JJ, Villalobos F, Ehrenstein V, Morton K, Rebordosa C, Ahmadizar F, Fortuny J, Arana A, Sturkenboom M.   +22 more
europepmc   +1 more source

The impact of medication shortages on paediatric care: A retrospective impact analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Medication shortages are a growing global concern, with potentially greater consequences in paediatric patients because of the limited availability of safe, evidence‐based and appropriately formulated medication. This study aimed to evaluate the impact of medication shortages on paediatric patients by assessing the suitability and safety of ...
Maaike Johanna Rutten ‐ van Kranenburg, Laurens Christiaan van Rijn, Elisabeth Johanna Ruijgrok, Sinno Henricus Paulus Simons, Brigitta Carolina Maria Witjes, Jan‐Dietert Christoffer Brugma, Robert Bernard Flint   +6 more
wiley   +1 more source

Do consumers and healthcare professionals report the same adverse event differently? A paired analysis of duplicate vaccine safety reports in Norway. [PDF]

Br J Clin Pharmacol
Dzus TE, Sarrage J, Samdal H, Montastruc F, Rocca E.   +4 more
europepmc   +1 more source

Efficacy and safety of vaccines

Veterinary Quarterly, 1994
openaire   +2 more sources

Capacity building in medicines development and regulation in Africa—Overview on recent progress

British Journal of Clinical Pharmacology, EarlyView.
Aims Despite advances in health research and digital innovation, many African countries continue to face substantial resource constraints, fragmented capacity‐building efforts and a shortage of skilled professionals in medicines development and regulatory science.
Tirhani Maluleke, Emile Malan, Michael Reid, Patrick Bouic, Haylene Nell, Goonaseelan Pillai, Catriona Waitt, Bernd Rosenkranz   +7 more
wiley   +1 more source

Vaccine Safety

, 2017
C. John Clements, Glenda L. Lawrence, Kristine K. Macartney   +2 more
openaire   +2 more sources

Pregnant Women and Vaccine Safety in Uganda: Knowledge, Barriers, and Opportunities for Engagement. [PDF]

Vaccines (Basel)
Nambasa VP, Komuhendo R, Serwanga A, Kajungu D, Koch BCP, Kampmann B, Le Doare K, Ssali A.   +7 more
europepmc   +1 more source