Results 121 to 130 of about 200,197 (308)

Polysaccharide-based self-assembling nanohydrogels: An overview on 25-years research on pullulan [PDF]

, 2015
The aim of this overview is to review the evolution of the studies carried out, during more than 25 years, on nanohydrogels obtained by self-assembling of pullulan (PUL) using several hydrophobization strategies.
ALHAIQUE, Franco, COVIELLO, Tommasina, DI MEO, Chiara, MATRICARDI, PIETRO, MONTANARI, ELITA   +4 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Brief communication: predictors of RSV vaccine uptake among older adults in South Dakota

Discover Public Health
In fall 2023, respiratory syncytial virus (RSV) vaccines became available to adults 60 years and older. In this brief communication, we reported the results of a survey of adults 60 years and older, which was fielded in November and December 2023 in ...
Filip Viskupič, David L. Wiltse
doaj   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Human papillomavirus vaccination uptake and determinant factors among adolescent schoolgirls in sub-Saharan Africa: A systematic review and meta-analysis

Human Vaccines & Immunotherapeutics
Despite the ongoing global vaccination campaign aimed at preventing human papillomavirus (HPV) related health issues, the uptake of the HPV vaccine remains unacceptably low in developing regions, particularly in sub-Saharan Africa (SSA).
Yordanos Sisay Asgedom, Tsegaye Melaku Kebede, Beminate Lemma Seifu, Kusse Urmale Mare, Zufan Alamrie Asmare, Hiwot Altaye Asebe, Bizunesh Fantahun Kase, Abdu Hailu Shibeshi, Tsion Mulat Tebeje, Kebede Gemeda Sabo, Bezawit Melak Fente, Afework Alemu Lombebo, Mengistu Meskele Koyira, Gizachew Ambaw Kassie   +13 more
doaj   +1 more source

Review of Varicella zoster virus : from epidemiology to prevention [PDF]

, 2008
The Varicella zoster virus is a human pathogen which causes Varicella after primary infection and herpes zoster after secondary reactivation. Both disease manifestations can occur at any age; however, Varicella is seen more commonly in children whilst ...
Pace, David
core  

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Trends of socioeconomic and geographic inequalities in COVID-19 vaccine uptake in Ethiopia: using the WHO Health Equity Assessment Toolkit

BMC Health Services Research
Background Equity in COVID-19 vaccine uptake is the heart of managing the ongoing pandemic of COVID-19 disease. However, the evidence of inequality in COVID-19 vaccination in Ethiopia is limited.
Abel Endawkie, Chala Daba, Lakew Asmare, Belay Desye, Temeselew Woldetsadik Mawugatie, Dagnachew Melak, Yawkal Tsega   +6 more
doaj   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

The Collaboration for Increasing Influenza Vaccination in Children (CIIVIC): a meeting report

Australian and New Zealand Journal of Public Health, 2021
Daniel A. Norman, Samantha J. Carlson, Jane Tuckerman, Jessica Kaufman, Hannah C. Moore, Holly Seale, Julie Leask, Helen Marshall, Catherine Hughes, Christopher C. Blyth, Margie Danchin, CIIVIC: The Collaboration for Increasing Influenza Vaccination in Children   +11 more
doaj   +1 more source