Results 71 to 80 of about 200,197 (308)

Cross-sectional survey of older peoples' views related to influenza vaccine uptake [PDF]

, 2006
BACKGROUND: The population's views concerning influenza vaccine are important in maintaining high uptake of a vaccine that is required yearly to be effective. Little is also known about the views of the more vulnerable older population over the age of 74
Punam Mangtani, Elizabeth Breeze, Sue Stirling, Smita Hanciles, Sari Kovats, Astrid Fletcher, J Ashley, TME Govaert, B Christensen, DM Fleming, P Mangtani, C Joseph, A Gupta, P Duclos, PO Honkanen, AJ Sievert, VE Burns, GA van Essen, AE Fletcher, P Mangtani, AE Fletcher, V Carstairs, S Corporation, P Mangtani, L Smeeth, P Mangtani, S Hull, J Watkins, AJ Arthur, CS Cornford, B Christensen, RL Petersen, E Breeze   +32 more
core   +4 more sources

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Missed Measles Immunisations Places Individuals and Communities at Risk: The Equity Argument for Including Measles in Under-Immunised Definitions

Vaccines
Background: Measles is consistently one of the leading causes of death from vaccine-preventable diseases in children, and cases and deaths have increased globally since 2019.
Stefanie Vaccher, Moses Laman, Margie Danchin, Fiona Angrisano, Christopher Morgan   +4 more
doaj   +1 more source

Single HA2 mutation increases the infectivity and immunogenicity of a live attenuated H5N1 intranasal influenza vaccine candidate lacking NS1 [PDF]

, 2011
Background: H5N1 influenza vaccines, including live intranasal, appear to be relatively less immunogenic compared to seasonal analogs. The main influenza virus surface glycoprotein hemagglutinin (HA) of highly pathogenic avian influenza viruses (HPAIV ...
Batishchev, Oleg V., Cinatl, Jindrich, Egorov, Andrej, Ferko, Boris, Geiler, Janina, Hinterdorfer, Peter, Humer, Johannes, Indenbom, Andrey V., Kastner, Markus, Kiefmann, Bettina, Kiselev, Oleg A., Krenn, Brigitte M., Michaelis, Martin, Morokutti, Alexander, Muster, Thomas, Nakowitsch, Sabine, Romanova, Julia, Romanovskaya-Romanko, Ekaterina, Ruthsatz, Tanja, Sturlan, Sanda, Wolschek, Markus, Wressnigg, Nina, Zhu, Rong   +22 more
core   +4 more sources

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

Advanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu, Zhiqi Cai, Xiangxin Sun, Hanyi Zhang, Yiming Hao, Jun Wu, Zekun Yan, Xue Wu, Yiqi Liang, Liming Wang, Songnan Qu   +10 more
wiley   +1 more source

Scaling-up vaccine production: implementation aspects of a biomass growth observer and controller [PDF]

, 2009
This study considers two aspects of the implementation of a biomass growth observer and specific growth rate controller in scale-up from small- to pilot-scale bioreactors towards a feasible bulk production process for whole-cell vaccine against whooping ...
Boxtel, A.J.B., van, IJssel, J., van den, Pol, L.A., van der, Soons, Z.I.T.A., Straten, G., van   +4 more
core   +2 more sources

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

Advanced Healthcare Materials, EarlyView.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter, Shashwat S. Agarwal, Joseph W. Tinapple, Joseph M. Barlage, Travis H. Jones, Jonathan W. Song   +5 more
wiley   +1 more source

The Impact of Age and Vaccine Conspiracy Beliefs on COVID-19 Vaccine Uptake among United States Adults

Vaccines
This observational study examined the relationships between age, vaccine conspiracy beliefs, and COVID-19 vaccine uptake in emerging adults (ages 20–30) and middle-aged adults (ages 50–60) residing in the United States.
Victoria A. Furlan, Brian N. Chin, Molly Menounos, Dina Anselmi   +3 more
doaj   +1 more source

Communication Interventions and Assessment of Drivers for Hendra Virus Vaccination Uptake

Vaccines, 2023
Hendra virus disease (HeVD) is an emerging zoonosis in Australia, resulting from the transmission of Hendra virus (HeV) to horses from Pteropus bats. Vaccine uptake for horses is low despite the high case fatality rate of HeVD in both horses and people ...
Jessica N. Kropich-Grant, Kerrie E. Wiley, Jennifer Manyweathers, Kirrilly R. Thompson, Victoria J. Brookes   +4 more
doaj   +1 more source