Results 251 to 260 of about 1,499,954 (350)

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Systematic review of evidence on feasibility of administering intranasal live attenuated influenza vaccine at home. [PDF]

NPJ Vaccines
Jhaveri R, Skolnik N, Bandell A.
europepmc   +1 more source

The Political Economy of Patent Buyouts

The RAND Journal of Economics, EarlyView.
ABSTRACT Incentivizing innovation through buyouts may alleviate the social costs associated with patent power, but the political economy and feasibility of this potentially important financing mechanism have been understudied. We study an international setting of countries with different innovation and financing capabilities, and where financing ...
Amal Ahmad, Dominik Naeher, Sebastian Vollmer   +2 more
wiley   +1 more source

Airborne transmission-mediated delivery of a live-attenuated influenza virus vector-based intranasal COVID-19 vaccine protects Syrian hamsters against SARS-CoV-2 challenge. [PDF]

NPJ Vaccines
Chen Y, Zhang L, Chen C, Yuan L, Han Q, Wang X, Chen H, Chen X, Wu R, Li Z, Han L, Lu Z, Wei D, Xia N, Chen J, Chen Y.   +15 more
europepmc   +1 more source

Development of a Cellular Membrane Nanovesicle-Based Vaccine Against Porcine Epidemic Diarrhea Virus. [PDF]

Cells
Wang X, Zhang W, Hu H, Gao W, Ma X, Wu Y, Qiao Y, Wang Y, Zhang D, Dong C, Wang H, Liu Z.   +11 more
europepmc   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Vaccination Against Respiratory Infections in Adults with Cancer: A Concise Guide for Clinicians. [PDF]

Vaccines (Basel)
See KC.
europepmc   +1 more source

Vaccinations During Pregnancy Protect the Mother–Infant Dyad and Are Generally Safe

Acta Paediatrica, EarlyView.
ABSTRACT Aim Vaccination in pregnancy has a critical impact on mothers, foetuses and infants. The aim of this paper was to summarise key points presented by experts attending the 12th Maria Delivoria‐Papadopoulos Perinatal Symposium in March 2025 and further expand and update them.
Ariadne Malamitsi‐Puchner, Despina D. Briana, Gian Carlo Di Renzo   +2 more
wiley   +1 more source

Nanoparticle-Based Antiviral Vaccines for Chickens: Recent Advances and Future Perspectives. [PDF]

Transbound Emerg Dis
Ding P, Xia L, Dong S.
europepmc   +1 more source

Construction and characterization of the ORF131 gene deletion strain of lumpy skin disease virus. [PDF]

Virol J
Li J, Huang W, Ke Q, Li M, Wang X, Wang Q, Yin X, Sun Y.   +7 more
europepmc   +1 more source