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Attenuation Methods for Live Vaccines
2020Vaccination was developed by Edward Jenner in 1796. Since then, vaccination and vaccine development research has been a hotspot of research in the scientific community. Various ways of vaccine development are successfully employed in mass production of vaccines. One of the most successful ways to generate vaccines is the method of virulence attenuation
Dipasree, Hajra +2 more
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Live-attenuated chikungunya virus vaccine
CellAlthough Chikungunya fever does not a have a high fatality rate (
Lisa F P, Ng, Laurent, Rénia
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Live Attenuated Varicella-Zoster Vaccine
Clinical Infectious Diseases, 1980Varicella-zoster (VZ) virus causes two diseases, varicella and zoster. Because it was recognized that, after varicella, latent VZ virus persisted in the host and because varicella was thought to be a milde disease, there was little impetus in North America to develop a live VZ vaccine.
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Live Attenuated Influenza Vaccine - A review
Journal of preventive medicine and hygiene, 2011Owing to the variability of influenza viruses, vaccine composition needs to be up-dated annually. As many variables can influence their efficacy, vaccines are still considered ?sub-optimal?. Many studies have been carried out in recent years to improve vaccines.
GASPARINI, ROBERTO +3 more
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Vaccination with Attenuated Measles-Virus Vaccine
American Journal of Diseases of Children, 1962The immunological efficacy and the absence of communicability of live attenuated measles-virus vaccine in children has been described by Katz and Enders 1 and by others 2-10 Since immunity to natural measles infection shortly after vaccination has also been reported, 3,4 the final acceptance of this vaccine for routine pediatric immunization will ...
P, HALONEN +6 more
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Vaccination against filarial worms using radiation-attenuated vaccines
International Journal of Nuclear Medicine and Biology, 1980This review covers the published work on attempts to vaccinate animals against filarial infections. There has been consistent success when dogs were vaccinated against Dirofilaria immitis using larvae irradiated with 15–20 krad. This was shown by a greatly reduced number of adult worms, which were also stunted and few or no microfilariae.
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Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron
Nature, 2022Huiping Shuai +2 more
exaly
Attenuated HIV Vaccine: Caveats
Science, 1996R M, Ruprecht, T W, Baba, V, Liska
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