Evaluating neoantigen-vaccine responses through mechanistic and model-based frameworks. [PDF]
Ibrahim EIK +7 more
europepmc +1 more source
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang +9 more
wiley +1 more source
Mucosal Delivery of Recombinant SARS-CoV-2 Spike Receptor-Binding Domain Antigen Containing Immune-Stimulating Peptides Induces Protective Immune Responses Against Viral Infection in huACE2 Mice. [PDF]
Cho BH, Kim J, Jang YS.
europepmc +1 more source
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley +1 more source
mGem: Progress on the development of conjugate vaccines for <i>Cryptococcus neoformans</i> infections. [PDF]
Stempinski PR +2 more
europepmc +1 more source
The Current Status of Simultaneous Vaccination of Children Aged 0-3 Years - China, 2022-2024. [PDF]
Liu X +10 more
europepmc +1 more source
BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu +12 more
wiley +1 more source
Conjugate Vaccines for Streptococcus pneumoniae
Peter R Paradiso
doaj +1 more source
Targeted pneumococcal conjugate vaccination strategies for high-risk children. [PDF]
Hart J +4 more
europepmc +1 more source
Pneumococcal Vaccines: The Impact of Conjugate Vaccine:Pneumococcal Vaccines: The Impact of Conjugate Vaccine [PDF]
openaire +1 more source

