Results 181 to 190 of about 39,539 (240)

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Availability of Hib, Pneumococcal, Rotavirus, and HPV vaccines in China: Implication for equity in access to immunization services. [PDF]

PLOS Glob Public Health
Guo L, Guo F, Jiang W, Zhang X, Dong D, Chen S, Wan Q, Tang S.   +7 more
europepmc   +1 more source

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Understanding adverse events following immunisation: evidence of vaccine safety and coincidental events from 3 years of surveillance. [PDF]

BMJ Paediatr Open
Mathew M, Sanathan SR, Ravi MD.
europepmc   +1 more source

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

Chemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu   +3 more
wiley   +1 more source

A Multi-Country Comparison of Number Needed to Vaccinate for PCV20 and PCV15 in Infants. [PDF]

Vaccines (Basel)
Dawson E, Tort MJ, Ta A, Rozenbaum MH.
europepmc   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović, Ingrid Tomljanović, Wieke H. Grievink, Diana R. Pereira, Michelle Osse, Peter van Balen, Maria J. Juachon, Marieke L. de Kam, Lisa Pagan, Manon A.A. Jansen, Matthijs Moerland, Jacobus J. Bosch   +11 more
wiley   +1 more source

PCV20 in pediatric pneumococcal prevention: expanded coverage, remaining challenges. [PDF]

Front Immunol
Principi N, Argentiero A, Campana B, Esposito S.   +3 more
europepmc   +1 more source

Measurement and Prediction of Unmixing‐Dependent Spreading due to Collinearity in Spectral Flow Cytometry

Cytometry Part A, EarlyView.
ABSTRACT Advances in spectral cytometry instrumentation and fluorescent reagents have led to the possibility of ultra‐high‐parameter panels exceeding 50 colors. However, panel size is limited in practice by unmixing‐dependent spreading (UDS), a phenomenon which leads to a progressive deterioration of unmixed signal‐to‐noise ratios in panels that ...
Peter L. Mage, Andrew J. Konecny, Florian Mair   +2 more
wiley   +1 more source

Safety and Immunogenicity of SII's 10-Valent Pneumococcal Conjugate Vaccine (PCV10-SII) in Vietnamese Children Aged from 6 Weeks to 24 Months: An Open-Label, Single-Arm Bridging Study. [PDF]

Vaccines (Basel)
Son VT, Anh BDT, Hoan VN, Than HV, Linh BK, Giang TH, Manh NT, Thao LTT, Cuong HX, Giang DT, Dat DT, Giang LTH, Mulay SC, Sethna V, Hung PV.   +14 more
europepmc   +1 more source