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Boosting with heterologous vaccines effectively improves protective immune responses of the inactivated SARS-CoV-2 vaccine

open access: yesEmerging Microbes and Infections, 2021
Since the outbreak of COVID-19, a variety of vaccine platforms have been developed. Amongst these, inactivated vaccines have been authorized for emergency use or conditional marketing in many countries.
Jialu Zhang   +18 more
doaj   +2 more sources

A Review of Inactivated COVID-19 Vaccine Development in China: Focusing on Safety and Efficacy in Special Populations

open access: yesVaccines, 2023
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been widespread globally, and vaccination is critical for preventing further spread or resurgence of the outbreak ...
Lidan Hu   +8 more
doaj   +2 more sources

Current Status of Vaccines for Porcine Reproductive and Respiratory Syndrome: Interferon Response, Immunological Overview, and Future Prospects

open access: yesVaccines
Porcine reproductive and respiratory syndrome (PRRS) remains a formidable challenge for the global pig industry. Caused by PRRS virus (PRRSV), this disease primarily affects porcine reproductive and respiratory systems, undermining effective host ...
Jiuyi Li, Laura C. Miller, Yongming Sang
doaj   +2 more sources

Inactivated Viral Vaccines

open access: yesVaccine Analysis: Strategies, Principles, and Control, 2014
Inactivated vaccines have been used for over a century to induce protection against viral pathogens. This established approach of vaccine production is relatively straightforward to achieve and there is an augmented safety profile as compared to their live counterparts.
Sanders, Barbara   +2 more
openaire   +2 more sources

Quality control procedure for Coccidial vaccines versus different routes of immunization [PDF]

open access: yesVeterinary World, 2022
Background and Aim: Coccidiosis is an enteric infection caused by a protozoon (Eimeria tenella). Coccidiosis is known to have a negative impact on the economy. Coccidiosis is controlled using anticoccidial drugs, antibiotics, and vaccines.
Arwa Elnaggar, Hala Mahmoud, Sahar Saber
doaj   +1 more source

Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults: A Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance Although effective vaccines against COVID-19 have been developed, additional vaccines are still needed. Objective To evaluate the efficacy and adverse events of 2 inactivated COVID-19 vaccines.
N. A. Al Kaabi   +40 more
semanticscholar   +1 more source

30-Year Development of Inactivated Virus Vaccine in China

open access: yesPharmaceutics, 2023
Inactivated vaccines are vaccines made from inactivated pathogens, typically achieved by using chemical or physical methods to destroy the virus’s ability to replicate.
Jinrong Shi   +4 more
doaj   +1 more source

Effectiveness of inactivated and Ad5-nCoV COVID-19 vaccines against SARS-CoV-2 Omicron BA. 2 variant infection, severe illness, and death

open access: yesBMC Medicine, 2022
Background Limited data are available on the effectiveness of inactivated and Ad5-nCoV COVID-19 vaccines in real-world use—especially against Omicron variants in SARS-CoV-2 infection-naïve population.
Zhuoying Huang   +13 more
semanticscholar   +1 more source

Effectiveness of Inactivated COVID-19 Vaccines Against Illness Caused by the B.1.617.2 (Delta) Variant During an Outbreak in Guangdong, China

open access: yesAnnals of Internal Medicine, 2022
Real-world evidence on inactivated COVID-19 vaccines against the SARS-CoV-2 B.1.617.2 (Delta) variant is limited. The authors of this cohort study analyzed vaccination, surveillance, screening, tracing, and quarantine data to determine the effectiveness ...
Min Kang   +14 more
semanticscholar   +1 more source

Analysis of COVID-19 Incidence and Severity Among Adults Vaccinated With 2-Dose mRNA COVID-19 or Inactivated SARS-CoV-2 Vaccines With and Without Boosters in Singapore

open access: yesJAMA Network Open, 2022
Key Points Question What is the rate and severity of COVID-19 in adult recipients of 2 or 3 doses of mRNA or inactivated SARS-CoV-2 vaccines? Findings In this cohort study including 2 441 581 individuals aged 30 years or more, the estimated effectiveness
O. Ng   +17 more
semanticscholar   +1 more source

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