Results 171 to 180 of about 80,375 (245)

Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

open access: yesEuropean Journal of Haematology, Volume 116, Issue 4, Page 336-349, April 2026.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot   +3 more
wiley   +1 more source

Glycosomal Phosphoenolpyruvate Carboxykinase CRISPR/Cas9‐Deletion and Its Role in Trypanosoma cruzi Metacyclogenesis and Infectivity in Mammalian Host

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Effects of PEPCK deficiency in Trypanosoma cruzi bioenergetics and life stages. ABSTRACT Trypanosoma cruzi, the causative agent of Chagas disease, possesses glycosomes—unique organelles that house key metabolic enzymes, several of which are promising therapeutic targets.
Carolina S. D. Vieira   +8 more
wiley   +1 more source

Development of a Self‐Adjuvanting Influenza Peptide–Glycolipid Conjugate Inducing CD8+ T‐Cell Immunity

open access: yesChemBioChem, Volume 27, Issue 5, 13 March 2026.
The glycolipid‐peptide antigen complexes for self‐adjuvanting conjugates were successfully synthesized, and, with the HLA‐transgenic mice, the antigen‐specific CD8+ T cell expansion was exhibited. The results provide useful insights for the design and synthesis of vaccine conjugates using glycolipid antigen as an adjuvant.
Shunya Kikuchi   +4 more
wiley   +1 more source

Sheep and goat pox: vaccines and vaccination scenarios to control the epidemics in Greece and Bulgaria in 2025. [PDF]

open access: yesEFSA J
European Food Safety Authority (EFSA)   +6 more
europepmc   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

open access: yesChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel   +2 more
wiley   +1 more source

Bluetongue in China: Current Status of Viruses, Vectors, Detection Methods, and Vaccines. [PDF]

open access: yesTransbound Emerg Dis
Xin J   +8 more
europepmc   +1 more source

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

open access: yesChemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito   +3 more
wiley   +1 more source

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