Abstract Introduction In 2025, the Medicines and Healthcare products Regulatory Agency (MHRA) approved the use of teplizumab (a monoclonal anti‐CD3 antibody) to delay progression from Stage 2 to Stage 3 Type 1 diabetes in the UK. Methods To address the need for clear guidance on managing patients eligible for teplizumab therapy, the British Society of ...
Renuka P. Dias +8 more
wiley +1 more source
Coxsackie B1 virus-like particle that lacks VP4 protein demonstrates improved vaccine scalability, stability and immunogenicity. [PDF]
Soppela S +13 more
europepmc +1 more source
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh +5 more
wiley +1 more source
Comparative Humoral Immune Responses Induced by Live-Attenuated and Inactivated Porcine Epidemic Diarrhea Vaccines in Replacement Gilts. [PDF]
Boonsoongnern P +8 more
europepmc +1 more source
Gamma‐irradiated Newcastle disease virus: an alternative inactivated oncolytic virotherapy
To overcome biological risks associated with using live NDV as an oncolytic therapy, we developed gamma‐NDV as a safer alternative. Using a murine model for skin cancer, we show that intratumor administration of gamma‐NDV outperformed live‐NDV in terms of reducing tumor growth and improving overall animal survival. Abstract Newcastle disease virus (NDV)
Eve V Kennedy +10 more
wiley +1 more source
Safety, Immunogenicity, and Vaccine Compatibility of a Trivalent Inactivated In Ovo Nanovaccine Against Avian Colibacillosis in Broilers Under Commercial Hatchery Conditions. [PDF]
Scuotto A +8 more
europepmc +1 more source
Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi +4 more
wiley +1 more source
Identification of metabolic signatures of immune response following mRNA and inactivated vaccines against COVID-19: a systematic review. [PDF]
Wasilewski A, Serrafi A.
europepmc +1 more source
ABSTRACT Formalin‐inactivated vaccines are widely employed as a primary preventive strategy against red sea bream iridoviral disease (RSIVD), which poses a substantial economic threat to the aquaculture of rock bream (Oplegnathus fasciatus). However, conventional quantitative PCR (qPCR) cannot differentiate infectious virions from noninfectious vaccine
Sung‐Bin Moon +8 more
wiley +1 more source

