Results 221 to 230 of about 132,203 (308)

Glanders: Past, Present and Future of a Neglected Zoonosis as a Threat in Veterinary and Human Health

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This review displays a comprehensive overview of glanders, including aetiology, epidemiology, pathogenesis, diagnosis, control strategies and ongoing eradication programs. It has also reviewed differential diagnosis and treatment both in animals and humans as well as organism's antimicrobial properties.
Yahya Kanani   +2 more
wiley   +1 more source

Diagnostic Investigation of Two Cases of Oslerus osleri Infection in Dogs: Microscopic Challenges and Molecular Characterisation

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Two cases of young dogs with chronic cough were investigated, one with bronchoalveolar lavage for cytology, the other with endoscopic biopsy for histopathology. DNA was extracted from stained smears and from formalin paraffin‐embedded blocs, six primer pairs spanning the ribosomal RNA gene of O.
Jeremie Korchia   +6 more
wiley   +1 more source

Advances in Adjuvanted Rabies Vaccines. [PDF]

open access: yesVaccines (Basel)
Wang Y, Sun H, Wu Y.
europepmc   +1 more source

TGF‐β Inhibitor Potentiates Osimertinib‐Induced Anti‐Tumor Immunity in Egfr‐Mutant Lung Cancer

open access: yesCancer Science, Volume 117, Issue 5, Page 1260-1272, May 2026.
Osimertinib enhances CD8+ T cell activity but also upregulates immunosuppressive TGF‐β in Egfr‐mutant lung tumors. This study demonstrates that TGF‐β inhibition with nintedanib or vactosertib potentiates osimertinib‐induced CD8+ T cell–mediated immunity and reduce CD206+ macrophages. These findings provide a strong rationale for novel immunotherapeutic
Tadahiro Kuribayashi   +17 more
wiley   +1 more source

Targeting Inflammation and Immune Regulation in Chronic Inflammation Associated Cancers

open access: yesCancer Science, Volume 117, Issue 5, Page 1209-1222, May 2026.
Chronic inflammation sustains activation of key inflammatory pathways, including Nuclear factor kappa B (NF‐κB), Interleukin‐6‐signal transducer and activator of transcription 3 (IL6‐STAT3), Phosphoinositide 3‐kinase/Akt (PI3K/Akt), and Wingless/β‐catenin (Wnt/β‐catenin) signaling. This promotes immune dysregulation through the expansion and functional
Lawan Rabiu   +5 more
wiley   +1 more source

Current status on encephalitic alphavirus vaccines development: Advances, challenges, and global health perspectives. [PDF]

open access: yesInfect Med (Beijing)
Yang X   +8 more
europepmc   +1 more source

Molecular Mechanism of Caspase‐8–Dependent Interleukin‐18 Activation in Pancreatic Cancer Cells Induced by 5‐Fluorouracil and Nutrient Starvation

open access: yesGenes to Cells, Volume 31, Issue 3, May 2026.
Nutrient starvation triggers pyroptosis with cleavage of pro‐IL‐18 and GSDMD in pancreatic cancer cells, and treatment of 5‐FU enhances this process. As a result, active IL‐18 is released and leads to inflammation. ABSTRACT Interleukin‐18 (IL‐18) is a pro‐inflammatory cytokine, and higher IL‐18 expression in pancreatic tumors is associated with poor ...
Hiroki Kamino   +2 more
wiley   +1 more source

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