Results 111 to 120 of about 702,754 (301)

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

open access: yesAdvanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte   +21 more
wiley   +1 more source

Acknowledgement to Reviewers of Vaccines in 2019

open access: yesVaccines, 2020
Vaccines Editorial Office
doaj   +1 more source

Thermostability of vaccines / Artur Galazka [PDF]

open access: yes, 1998
WHO/GPV/98.0757 ...
Zaffran, Michel   +3 more
core  

Parenteral vaccination of mammalian livestock with Newcastle disease virus-based vector vaccines offers optimal efficacy and safety [PDF]

open access: yes, 2011
Newcastle disease virus (NDV) is an avian virus that is being evaluated as a vaccine vector for the delivery of foreign genes in mammals. The use of NDV as a vaccine vector in these species offers two major advantages.
Adriaan F.G. Antonis   +7 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Boosting neuraminidase immunity in the presence of hemagglutinin with the next generation of influenza vaccines

open access: yesnpj Vaccines
Neuraminidase (NA), the second most abundant surface glycoprotein on the influenza virus, plays a key role in viral replication and propagation. Despite growing evidence showing that NA-specific antibodies correlate with resistance to disease in humans ...
Guadalupe Cortés   +17 more
doaj   +1 more source

Self‐Feeding Living Materials Enabled by Cell Responsive Glycogen Nanoparticles as Metabolic Batteries

open access: yesAdvanced Materials, EarlyView.
Glycogen is introduced as a metabolic battery that offers local and cell‐triggered release of glucose. Glycogen can be stably encapsulated into hydrogel (Dex‐TA) microcapsules that allow for diffusion of glycogen‐degrading enzymes and nutrients.
Melvin Gurian   +8 more
wiley   +1 more source

CPP–PEG‐Guided Surface Engineering of Mitochondria Enables Efficient Cellular Uptake and Respiratory Modulation

open access: yesAdvanced Materials Interfaces, EarlyView.
PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi   +9 more
wiley   +1 more source

VACCINATION. [PDF]

open access: yesThe Lancet, 1885
n ...
openaire   +2 more sources

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