Results 111 to 120 of about 702,754 (301)
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte +21 more
wiley +1 more source
Acknowledgement to Reviewers of Vaccines in 2019
Vaccines Editorial Office
doaj +1 more source
Thermostability of vaccines / Artur Galazka [PDF]
WHO/GPV/98.0757 ...
Zaffran, Michel +3 more
core
Parenteral vaccination of mammalian livestock with Newcastle disease virus-based vector vaccines offers optimal efficacy and safety [PDF]
Newcastle disease virus (NDV) is an avian virus that is being evaluated as a vaccine vector for the delivery of foreign genes in mammals. The use of NDV as a vaccine vector in these species offers two major advantages.
Adriaan F.G. Antonis +7 more
core +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Neuraminidase (NA), the second most abundant surface glycoprotein on the influenza virus, plays a key role in viral replication and propagation. Despite growing evidence showing that NA-specific antibodies correlate with resistance to disease in humans ...
Guadalupe Cortés +17 more
doaj +1 more source
Glycogen is introduced as a metabolic battery that offers local and cell‐triggered release of glucose. Glycogen can be stably encapsulated into hydrogel (Dex‐TA) microcapsules that allow for diffusion of glycogen‐degrading enzymes and nutrients.
Melvin Gurian +8 more
wiley +1 more source
PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi +9 more
wiley +1 more source

