Results 141 to 150 of about 806,967 (237)

The efficacy and effectiveness of enterovirus A71 vaccines against hand, foot, and mouth disease: A systematic review and meta-analysis. [PDF]

PLoS One
Yan X, Liu Y, Chen F, Chang Z, Zhang Z, Pons-Salort M, Grassly NC.   +6 more
europepmc   +1 more source

A Smart Single‐Loop‐Mediated Isothermal Amplification Facilitates Flexible SNP Probe Design for On‐Site Rapid Differentiation of SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
The ssLAMP method amplifies the nucleic acid of pathogen and identifies SNP mutations. By combining the portable detection device with smartphone‐based analysis software, enables rapid, on‐site SNP detection and genotyping of SARS‐Cov‐2 Omicron variants, providing a cost‐effective and field‐deployable solution for precise pathogen identification in ...
Qijie Lin, Hongchao Gou, Xiaoyun Qu, Kaiyuan Jia, Yuhui Deng, Dan Li, Qianyi Cai, Yucen Liang, Xiaozhen Xu, Yanbin Li, Jianhan Lin, Letian Li, Yuhang Jiang, Shouwen Du, Lingcong Deng, Bailing Yan, Ruidong Liu, Chang Li, Jianmin Zhang, Ming Liao   +19 more
wiley   +1 more source

Coverage disparities and delayed immunization: Assessing 12-month vaccination completion in Canadian children using data from a digital immunization platform. [PDF]

Hum Vaccin Immunother
Serhan M, Nilormi A, Ntacyabukura B, Atkinson K, Ducharme R, Hawken S, Ramsay T, Ang J, Wilson K.   +8 more
europepmc   +1 more source

Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine

Advanced Science, EarlyView.
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li, Huiqin Chen, Qiaofeng Shen, Yingshuang Liu, Pingping Li, Yuqi Ma, Yugang Wang, Shengkai Li, Xueqing Yan, Liyu Liu, Jianwei Shuai, Min Wu, Qi Ouyang, Feng‐Ming (Spring) Kong, Gen Yang   +14 more
wiley   +1 more source

“Confined Eutectic” Strategy for Visual Refrigeration Responsive Fluorescent Materials with Easy Preparation and Multi‐Color Tunability

Advanced Science, EarlyView.
A new strategy of “confined eutectic” is proposed to achieve fluorochromic materials that can readout refrigeration temperature with naked‐eye. It leverages changes in the crystallinity of the confined eutectics in nano/micro‐domains to regulate the aggregation and dispersion states of fluorophores.
Jifang Zhao, Jiahui Du, Tianyou Qin, Sean Xiao‐An Zhang, Lan Sheng   +4 more
wiley   +1 more source

Evaluation of broad-spectrum protection by novel mRNA vaccines against SARS-CoV-2 variants (Delta, Omicron-BA.5, XBB-EG.5) in the golden hamster model. [PDF]

Virol J
Yu T, Xing J, Zhuang X, Tian M.
europepmc   +1 more source

Vaccine and Vaccination

American Journal of Public Health and the Nations Health, 1930
openaire   +3 more sources

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

Advanced Science, EarlyView.
Cryo‐inactivated cancer cell‐based magnetic micromotors are developed for synergistic tumor immunotherapy via magnetic targeting. These micromotors can induce ferroptosis and immunogenic cell death, deliver tumor antigens, and activate the Mn2+‐dependent cGAS‐STING pathway. The system effectively suppresses tumor progression, recurrence, and metastasis,
Qingfei Zhang, Gaizhen Kuang, Wenzhao Li, Yuanjin Zhao   +3 more
wiley   +1 more source

Nucleic acid vaccines: innovations, efficacy, and applications in at-risk populations. [PDF]

Front Immunol
Konopka EN, Edgerton AO, Kutzler MA.
europepmc   +1 more source

Engineered Bacterial Outer Membrane Vesicles Hitchhiking on Neutrophils for Antibody Drug Delivery to Enhance Postoperative Immune Checkpoint Therapy

Advanced Science, EarlyView.
This study employs neutrophils for the precise delivery of anti‐CD47 antibodies, combined with bacterial outer membrane vesicles, to enhance macrophage phagocytic function in the tumor microenvironment. This approach effectively activates T‐cell anti‐tumor immune responses and significantly reduces the risk of postoperative tumor recurrence and ...
Meng Guan, Xiao‐Ting Xie, Dong Zhou, Kai Cheng, Bin Zhang, Xin‐Yue Xu, Yong Li, Yi‐Tong Zhou, Wei Peng, Li‐Li Chen, Peng‐Shuo Dong, Si Chen, Jia‐Hua Zou, Bo Liu, Yuan‐Di Zhao, Jin‐Xuan Fan   +15 more
wiley   +1 more source