Results 281 to 290 of about 714,773 (317)

Lessons for medical countermeasure development from unforeseen outbreaks. [PDF]

Emerg Microbes Infect
Mura M, Trignol A, Le Dault E, Tournier JN.   +3 more
europepmc   +1 more source

Roadmap to Nanomedical Applications: Nanotoxicology and In Vitro Guidelines for Lanthanide‐Doped Luminescence Nanothermometers

Advanced NanoBiomed Research, EarlyView.
Lanthanide‐based luminescence nanothermometry holds multifaceted potential for nanomedical applications, yet despite significant research advances, clinical translation of the engineered nanomaterials is still controversial and widely disputed. This is related to crucial nanotoxicological aspects that must be addressed at the preclinical level ...
Simona Premcheska, Andre G. Skirtach, Anna M. Kaczmarek   +2 more
wiley   +1 more source

T and B cell responses in different immunization scenarios for COVID-19: a narrative review. [PDF]

Front Immunol
Piano Mortari E, Ferrucci F, Zografaki I, Carsetti R, Pacelli L.   +4 more
europepmc   +1 more source

Two doses of Qβ virus like particle vaccines elicit protective antibodies against heroin and fentanyl. [PDF]

NPJ Vaccines
Romano IG, Johnson-Weaver B, Core SB, Jamus AN, Brackeen M, Blough B, Dey S, Huang Y, Staats H, Wetsel WC, Chackerian B, Frietze KM.   +11 more
europepmc   +1 more source

High‐fidelity in vitro packaging of diverse synthetic cargo into encapsulin protein cages

Angewandte Chemie International Edition, Accepted Article.
Cargo‐filled protein cages are powerful tools in biotechnology with demonstrated potential as catalytic nanoreactors and vehicles for targeted drug delivery. While endogenous biomolecules can be packaged into protein cages during their expression and self‐assembly inside cells, synthetic cargo molecules are typically incompatible with live cells and ...
Taylor Szyszka, Rezwan Siddiquee, Alex Loustau, Lachlan S. R. Adamson, Claire Rennie, Tiancheng Huang, Reginald Young, Andrew Care, Yu Heng Lau   +8 more
wiley   +1 more source

Identification of an Activity Selector for the Nitroso‐Forming Activity in Bacterial Type‐III Copper Enzymes

Angewandte Chemie International Edition, Accepted Article.
O‐aminophenol oxidases, a specialized subclass of type‐III copper proteins, play a crucial role in the biosynthesis of bioactive nitrosophenols which display antiretroviral and blood cholesterol lowering activity. Another related subclass of type‐III copper proteins, tyrosinases, closely resemble o‐aminophenol oxidases both structurally and ...
Hoa Le Xuan, Felix Panis, Annette Rompel
wiley   +1 more source

Differential efficacy of first licensed western vaccines protecting without immunopathogenesis Wuhan-1-challenged hamsters from severe COVID-19. [PDF]

NPJ Vaccines
Ebenig A, Lange MV, Gellhorn Serra M, Kupke A, Plesker R, Qu B, Brown RJP, Maier TJ, Mühlebach MD.   +8 more
europepmc   +1 more source

Catch, Cut, or Block? – Versatile 4‐N‐Derivatized Sialyl Glycosides for Influenza Virus Neuraminidase Detection and Purification

Angewandte Chemie International Edition, Accepted Article.
Seasonal influenza continues to threaten human lives and pose a significant burden to healthcare systems and the economy, emphasizing the need for developing better influenza vaccines, diagnostics, and anti‐viral therapeutics. To address these challenges, we generated a library of structurally diverse sialyl glycosides containing 4‐N‐derivatized sialic
Yue Yuan, Hai Yu, Anand Kumar Agrahari, Jin Gao, Hyeog Kang, Robert Daniels, Xi Chen   +6 more
wiley   +1 more source

Clinical and evidence-based considerations for choosing a pneumococcal conjugate vaccine in India: A narrative review. [PDF]

Hum Vaccin Immunother
Yewale V, Chatterjee P, Marathe SM, Taur S, Sathyanarayanan S.   +4 more
europepmc   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, Accepted Article.
Supported by rapid technological advancements, biocatalytic applications have matured into a sustainable, scalable, and cost‐competitive alternatives to established chemical catalysis. This review presents the most recent examples of enzyme‐based solutions for the manufacturing of molecules with extended carbon‐carbon frameworks and multiple ...
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe Bornscheuer   +4 more
wiley   +1 more source