Results 131 to 140 of about 98,253 (278)

Efficacy of the modified vaccinia Ankara virus vaccine and the replication-competent vaccine ACAM2000 in monkeypox prevention

, 2023
Mahmoud Kandeel, Mohamed A. Morsy, Hany M. Abd El‐Lateef, Mohamed Marzok, Hossam S. El‐Beltagi, Khalid M. Al Khodair, Ibrahim Albokhadaim, Katharigatta N. Venugopala   +7 more
openalex   +1 more source

VRK1 Is a Novel Therapeutic Target for Small Cell Neuroendocrine Carcinoma of the Cervix

Cancer Science, Volume 117, Issue 1, Page 78-89, January 2026.
Small cell neuroendocrine carcinoma of the cervix (SCNEC), a rare but aggressive cancer, consistently exhibited high VRK1 expression. VRK1 knockdown significantly suppressed xenograft tumor growth by inducing mitochondrial dysfunction. These findings highlighted VRK1 as a potential therapeutic target for SCNEC.
Mariya Kobayashi, Satoshi Nakagawa, Yusuke Ishii, Yuji Kamei, Mizuki Kanda, Tatsuo Masuda, Mamoru Kakuda, Kosuke Hiramatsu, Tadashi Iwamiya, Tomomi Egawa‐Takata, Shinya Matsuzaki, Hiroyuki Uematsu, Kunishige Onuma, Masahiro Inoue, Yutaka Ueda, Tadashi Kimura, Michiko Kodama   +16 more
wiley   +1 more source

A prime/boost DNA/Modified vaccinia virus Ankara vaccine expressing recombinant Leishmania DNA encoding TRYP is safe and immunogenic in outbred dogs, the reservoir of zoonotic visceral leishmaniasis [PDF]

Previous studies demonstrated safety, immunogenicity and efficacy of DNA/modified vaccinia virus Ankara (MVA) prime/boost vaccines expressing tryparedoxin peroxidase (TRYP) and Leishmania homologue of the mammalian receptor for activated C kinase (LACK ...
Alcami, Antonio, Antoniou, Maria, Begoña Ruiz-Argüello, Maria, Blackwell, Jenefer M., Carson, Connor, Christodoulou, Vasiliki, Courtenay, Orin, Messaritakis, Ippokratis   +7 more
core   +1 more source

Safety and Efficacy of Plant‐Produced Trivalent Virus‐Like Particle Vaccine Candidate Against Bluetongue Disease

Plant Biotechnology Journal, Volume 24, Issue 1, Page 273-283, January 2026.
ABSTRACT Bluetongue (BT) is a non‐contagious, insect‐transmitted disease of wild and domestic ruminants caused by bluetongue virus (BTV). Effective control of BT disease relies on vaccination against prevalent or seasonal serotypes using live attenuated or inactivated vaccines.
Tendai A. M. Mlingo, Martha M. O'Kennedy, Matome Matsiela, Ntombikayise Nkomo, Peter Coetzee, Thapelo Rametse, Paidamwoyo Mutowembwa, Livio Heath, Nobalanda Mokoena   +8 more
wiley   +1 more source

The Impact of Monkeypox Virus Infection on Pregnancy Outcome: Clinical Features and Potential Pathogenic Mechanisms

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Monkeypox has garnered significant attention following its emergence in multiple countries and its designation as a global health emergency in 2022. There is a notable deficiency in clinical and experimental data regarding pregnancy outcomes following monkeypox infection.
Jingyi Wu, Fangbin Huang, Qingliang Zheng, Poorani Gurumallesh   +3 more
wiley   +1 more source

Detection of antibody-dependent complement mediated inactivation of both autologous and heterologous virus in primary HIV-1 infection [PDF]

, 2005
Specific CD8 T-cell responses to human immunodeficiency virus type 1 (HIV-1) are induced in primary infection and make an important contribution to the control of early viral replication.
Aasa-Chapman, M.M.I., Aubin, K., Borrow, P., Cornforth, D., Holuigue, S., Jones, N.A., McKnight, A., Newton, P., Pellegrino, P., Williams, I., Wong, M.   +10 more
core  

Vaccinia virus transcription

Journal of General Virology, 2003
Vaccinia virus replication takes place in the cytoplasm of the host cell. The nearly 200 kbp genome owes part of its complexity to encoding most of the proteins involved in genome and mRNA synthesis. The multisubunit vaccinia virus RNA polymerase requires a separate set of virus-encoded proteins for the transcription of the early, intermediate and late
openaire   +2 more sources

Induction of Protein Kinase PKR-dependent Activation of Interferon Regulatory Factor 3 by Vaccinia Virus Occurs through Adapter IPS-1 Signaling [PDF]

, 2008
Ping Zhang, Charles E. Samuel
openalex   +1 more source

Generalized Vaccinia [PDF]

BMJ, 1943
openaire   +2 more sources

CD40 ligand‐expressing recombinant vaccinia virus promotes the generation of CD8⁺ central memory T cells [PDF]

, 2015
Emanuele Trella, Nermin Raafat, Chantal Mengus, Emmanuel Traunecker, Valeria Governa, Swantje Heidtmann, Michael Heberer, Daniel Oertli, Giulio C. Spagnoli, Paul Zajac   +9 more
openalex   +1 more source