Results 41 to 50 of about 2,375 (180)
Hansenologia Internationalis: hanseníase e outras doenças infecciosas, 1998 A única vacina contra a hanseníase já aprovada para uso humano é o uso de Mycobacterium bovis BCG, utilizada primariamente contra a tuberculose. Entretanto, a eficácia desta vacina contra a hanseníase é bastante variável na literatura científica. Desta forma, a pesquisa de outras vacinas com resultados mais reprodutíveis permanece.
João Renato Rebello Pinho +2 more
openaire +2 more sources
Cytotoxic Signature and IFN‐γ Production Dominate CD4+ T‐Cell Response During Human Toxoplasmosis
Immunology, Volume 175, Issue 2, Page 151-164, June 2025.Overview of CD4+ T‐cell subsets in patients with toxoplasmosis. Schematic drawing summarising the most important alterations in CD4+ T‐cell subsets, illustrated in different colours, from patients in distinct stages of toxoplasmosis, represented with different colours, with (lesion) or without (no lesion) ocular manifestations.
Priscilla Miranda Henriques +14 more
wiley +1 more source
HLA, Volume 105, Issue 6, June 2025.ABSTRACT The aim of this study was to investigate the influence of HLA‐A, ‐B and ‐C polymorphisms on the clinical course of SARS‐CoV‐2 infection and on the progression of COVID‐19 in a population from southeastern Brazil. This study included 478 unvaccinated individuals. Of these, 369 were hospitalised with critical/severe (n = 309) or moderate/mild (n
Christiane Maria Ayo +8 more
wiley +1 more source
Evaluation of binding activities of a putative lipoprotein LIC_13355 of Leptospira spp.
FEBS Open Bio, Volume 15, Issue 3, Page 447-461, March 2025.Pathogenic Leptospira causes leptospirosis, a severe zoonotic infection. Despite its impact, the infection mechanisms are unclear and likely multifactorial. We identify a putative lipoprotein, LIC_13355, conserved among pathogenic Leptospira spp. The recombinant protein rLIC_13355 interacts with extracellular matrix laminin and binds plasminogen ...
Igor R. M. Silva +3 more
wiley +1 more source
Immunity, Inflammation and Disease, Volume 12, Issue 7, July 2024.We generated a new trimeric recombinant continuously expressed in HEK‐293 cells corresponding to the receptor binding domain and the C‐terminus of S1 protein SARS‐Cov2. It was able to generate neutralizing antibodies and suitable for diagnostic procedures of Covid‐19.
Veronica A. de Lima +11 more
wiley +1 more source
Revista do Instituto de Medicina Tropical de São Paulo, 2009 Objective: to discuss the current PAHO recommendation that does not support the substitution of traditional cellular DTP vaccine by acellular DTP, and the role of mutations, in humans, as the main cause of rare adverse events, such as epileptic-like ...
Hisako G. Higashi +6 more
doaj +1 more source
Highly Atypical 2025 Influenza A Season in Brazil
Influenza and Other Respiratory Viruses, Volume 20, Issue 4, April 2026.
Tatiana P. Portella +4 more
wiley +1 more source
Ciência Rural, 2005 Os títulos e duração de anticorpos neutralizantes contra o vírus da Diarréia Viral Bovina (BVDV) induzidos por uma vacina experimental atenuada (vacina A: dose única) foram comparados com os induzidos por três vacinas comerciais inativadas (B, C e D ...
Marcelo de Lima +3 more
doaj +1 more source
Lesões vacinais na carcaça de bovinos no Norte de Minas Gerais
Pubvet, 2019 Objetivou-se quantificar o as reações vacinais em bovinos de corte. A pesquisa foi desenvolvida na fazenda Fundinho, localizada no município de Jaíba/MG e Fazenda Experimental da Unimontes, localizada na cidade de Janaúba/MG.
José Eduardo Jardim Murta +5 more
doaj +1 more source
Resposta imunológica em caprinos vacinados contra agalaxia contagiosa
Pesquisa Veterinária Brasileira, 2013 Este trabalho teve como objetivo avaliar a eficiência de duas vacinas inativadas contra agalaxia contagiosa contendo adjuvante oleoso e aquoso. Para tanto, foram utilizados 73 caprinos, agrupados em dois experimentos.
Maria Dalva B. Alcântara +7 more
doaj +1 more source