Results 121 to 130 of about 406,286 (313)

Loss of the putative Rab GTPase, Ypt7, impairs the virulence of Cryptococcus neoformans

open access: yesFrontiers in Microbiology
Small GTPases of the Rab family coordinate multiple membrane fusion and trafficking events in eukaryotes. In fungi, the Rab GTPase, Ypt7, plays a critical role in late endosomal trafficking, and is required for homotypic fusion events in vacuole ...
Guanggan Hu   +11 more
doaj   +1 more source

Cell-free reconstitution of vacuole membrane fragmentation reveals regulation of vacuole size and number by TORC1.

open access: yes, 2012
Size and copy number of organelles are influenced by an equilibrium of membrane fusion and fission. We studied this equilibrium on vacuoles-the lysosomes of yeast.
Michaillat, L., Baars, T.L., Mayer, A.
core   +1 more source

The Diagnostic Value of Immunohistochemistry and Biomarkers in the Diagnosis of Mesothelioma in Pleural/Peritoneal Effusions

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Background Mesothelioma is a rare tumor that arises from the serosal cells lining the serous cavities, most commonly the pleura followed by the peritoneum. Presenting symptoms include pleuritic pain and bloody effusions that recur. Although cytologic analysis cannot determine the mesothelial subtype or in situ from invasive disease, the ...
Suzanne M. Selvaggi
wiley   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin   +5 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Geometry of the vacuole.

open access: yes, 2015
Left: a cell represented for computational purposes as a brick shape with a square cross section. The vacuole is in blue. Measurements in microns. Right: we consider lateral coupling in the horizontal direction.
Graeme Mitchison (816148)
core   +1 more source

Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Beyond follicular‐derived thyroid carcinomas, lymphomas, and metastatic disease, there are rare pathologies of the thyroid gland that represent a challenge. We report patients with unusual malignancies that mimic similar aggressive cancers. Methods Retrospective case series.
David Z. Allen   +12 more
wiley   +1 more source

Treating the vacuole and cytoplasm as channels.

open access: yes, 2015
The vacuole (red) can be regarded as an apolar channel coupled to the cytosol (blue).
Graeme Mitchison (816148)
core   +1 more source

Symbiotic Germination Technique of an Endangered Epiphytic Orchid Dendrobium sinominutiflorum: A Promising Conservation Application 濒危附生兰科植物勐海石斛 (Dendrobium sinominutiflorum) 的共生萌发技术:一种具有应用前景的保护策略

open access: yesIntegrative Conservation, EarlyView.
We developed an effective ex‐situ conservation approach for an endangered orchid species, Dendrobium sinominutiflorum. A compatible fungal strain Tulasnella sp. was obtained by using in‐situ seed baiting technique. The Symbiotic germination with Tulasnella sp. significantly promotes seed germination and seedling growth.
Han‐Xiao Huang   +6 more
wiley   +1 more source

Vesicular trafficking into the plant vacuole

open access: yes, 2013
Vacuole is very important plant cell organelle which can occupy 90% of cell volume. It provides wide range of functions. Considering enormous size of the vacuole, vesicle trafficking into the plant vacuole is major vesicle movement inside the cell ...
Semerádová, Hana
core  

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