Results 121 to 130 of about 425,388 (212)

NOXA/MCL-1 axis determines cell-death decision between apoptosis and a GSDME-dependent cell death associated with production of inflammatory cytokines upon treatment of breast cancer cells with antimitotics. [PDF]

Cell Death Dis
Dumont A, Gautier F, Josso V, Batard Q, Moreau A, Campone M, Juin P, Barillé-Nion S.   +7 more
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Mitochondria-lysosome coupling contributes to lysosome acidification and aging. [PDF]

Mol Cell
Liu Q, Yoo S, Zhang ZA, Li L, Su H, Vannur L, Wooldredge AC, Hughes JB, Desprez PY, Hao N, Lithgow G, Andersen JK, Hansen M, Campisi J, Zhou C.   +14 more
europepmc   +1 more source

Resource competition between buoyancy‐regulating and sinking phytoplankton species along a stratified water column

Oikos, EarlyView.
In temperate lakes, plankton dynamics are closely linked to seasonal shifts in water stratification, following air temperature. The onset of summer stratification typically coincides with the formation of an algal spring bloom in the well‐mixed surface layer (epilimnion).
Arthur F. Rossignol, Sabine Wollrab
wiley   +1 more source

Coupling Vgll4b/Yap-regulated posterior cell addition with anterior vacuolation enables robust notochord elongation. [PDF]

Development
Camacho-Macorra C, Ceccarelli AS, Serrano Nájera G, Saunders D, Boesgaard I, Chara O, Steventon B.   +6 more
europepmc   +1 more source

A Comparison of Homologous Proteins in Homotypic Vacuole Fusion

https://rdc.reed.edu/v1/resources/ee17d7f8-4572-4e14-877d-a8c716d2b3b3/thumb/128.jpgThe vast majority of research on homotypic vacuole fusion has been performed using S. cerevisiae models. However, the process of homotypic vacuole fusion is vital for the
O'Brien, Aden
core  

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

PROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima, Wilson Dias Segura, Leonardo Brogliato de Moraes, Reinaldo Souza Oliveira, Pedro Henrique Corteletti Manfio, Alison Felipe Alencar Chaves, Wagner Luiz Batista   +6 more
wiley   +1 more source

Effects of Ammonium Chloride-Mediated Control of Digestive Vacuole Acidification on Endosymbiosis Between <i>Paramecium tritobursaria</i> and <i>Chlorella variabilis</i>. [PDF]

Microorganisms
Uchida N, Kodama Y.
europepmc   +1 more source

Nutritional properties, traditional uses and potential new applications for the sotol plant (Asparagaceae, Convallarioideae): A review

PLANTS, PEOPLE, PLANET, EarlyView.
Sotol (Dasylirion spp.) is a resilient desert plant that sustains ecosystems, cultures and livelihoods in Chihuahua Desert. Our review highlights its nutritional properties, traditional uses and potential new applications in food, pharmaceuticals, renewable energy and water remediation. By synthesizing evidence across disciplines, we show how sotol can
Dámaris Leopoldina Ojeda Barrios, Antonio Martínez Ruiz, Marisela Calderón Jurado, Ramón Saúl Luján Aguirre, Juan Luis Jacobo Cuellar, Oscar Sariñana‐Aldaco, María Teresa Martínez Damián, Oscar Cruz Alvarez   +7 more
wiley   +1 more source

Treatment of <i>Saccharomyces cerevisiae</i> with cigarette smoke extract causes vacuolar fragmentation to combat cigarette smoke-induced cellular toxicity. [PDF]

Front Toxicol
Shukla A, Sarkar S, Sil AK.
europepmc   +1 more source