Results 101 to 110 of about 406,286 (313)
The Vacuole Lipid Droplet Contact Site vCLIP
Lipid droplets frequently form contact sites with the membrane of the vacuole, the lysosome-like organelle in yeast. These vacuole lipid droplet (vCLIP) contact sites respond strongly to metabolic cues: while only a subset of lipid droplets is bound to ...
Duy Trong Vien Diep +3 more
core +1 more source
Unraveling a Diagnostic Enigma: A TECPR2 Case Solved Through Multi‐Omic Genomics
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT TECPR2 is a key regulator of autophagy, encoded by the TECPR2 gene. Pathogenic variants in this gene have been linked to a rare hereditary sensory and autonomic neuropathy with intellectual disability (HSAN9). We report a teenage female with a syndromic intellectual disability disorder associated with neuromuscular abnormalities.
Teresa Zhao +122 more
wiley +1 more source
DYSREGULATION OF ION HOMEOSTASIS BY ANTIFUNGAL AGENTS
Frontiers in Microbiology, 2012 Ion signaling and transduction networks are central to fungal development and virulence because they regulate gene expression, filamentation, host association and invasion, pathogen stress response and survival.
Yongqiang eZhang +2 more
doaj +1 more source
GO term of fungal-type vacuole membrane.
, 2015 Fungal-type vacuole membrane is vacuole membrane, it is the organelle membrane which belongs to cellular component. Being the largest organelles in cells of eukaryotic microorganisms, vacuoles are known to function in intracellular ion homeostasis ...
Guo-Lian Bao (723387) +5 more
core +1 more source
SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells
Animal Models and Experimental Medicine, EarlyView.The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang +6 more
wiley +1 more source
, 2019 Over the past 9 years I have worked with artists who have used various media to portray the process of autophagy. This has included paintings, protein music, a piano composition, a wood sculpture, a quilt, and a dance. Here, I describe a two-part project
Scott Hartley (6953780) +1 more
core +1 more source
The Anatomical Record, EarlyView.Abstract Scientists have been captivated by the ability to regenerate, focusing on uncovering the mechanisms of epimorphic regeneration and applying them to human medicine. The axolotl (Ambystoma mexicanum) has become the most intensively studied model in tetrapod regeneration research, particularly concerning limb regeneration.
Vivien Bothe, Nadia Fröbisch
wiley +1 more source
The Anatomical Record, EarlyView.Abstract The equine ovary exhibits unique structural and developmental features that distinguish it from those of other domestic species, including the presence of an ovulation fossa and an inversion of cortical and medullary layers. This study aimed to investigate the morphostructural development of the equine fetal ovary, with particular emphasis on ...
Laura Ver Goltz +5 more
wiley +1 more source
Endolysosomal pathway activity protects cells from neurotoxic TDP-43
Microbial Cell, 2018 The accumulation of protein aggregates in neurons is a typical pathological hallmark of the motor neuron disease amyotrophic lateral sclerosis (ALS) and of frontotemporal dementia (FTD).
Christine Leibiger +7 more
doaj +1 more source