Results 91 to 100 of about 406,286 (313)
Membrane protein degradation is intrinsic to vacuole fusion [PDF]
, 2013 In eukaryotic cells, integral membrane protein (IMP) turnover is an important contributor to cell physiology. Whereas the only known mechanism for IMP degradation is the multivesicular body (MVB) pathway, there are examples of IMPs that eschew this ...
Richard, Joël D.
core
, 2019 Logarithmic-phase cells of C. glabrata were prepared in SC broth. Vacuolar membranes were first stained with FM4-64. After washing, the pH-sensitive fluorophore BCECF-AM was added to cell suspensions.
Hironobu Nakayama (278861) +12 more
core +1 more source
Advanced Science, EarlyView.Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An +8 more
wiley +1 more source
eLife, 2018 The ubiquitin-like protein Atg8, in its lipidated form, plays central roles in autophagy. Yet, remarkably, Atg8 also carries out lipidation-independent functions in non-autophagic processes. How Atg8 performs its moonlighting roles is unclear.
Xiao-Man Liu +8 more
doaj +1 more source
Vacuole development in evacuolated oat mesophyll protoplasts
, 1994 Protoplasts were prepared from oat leaf mesophyll cells and subsequently evacuolated by high speed centrifugation through a continuous Percoll gradient.
Newell, Jane Marie, Newell, J. M.
core
The Coxiella burnetii parasitophorous vacuole
, 2012 Coxiella burnetii is a bacterial intracellular parasite of eucaryotic cells that replicates within a membrane-bound compartment, or “parasitophorous vacuole” (PV).
Ghigo, Eric +5 more
core +1 more source
Advanced Intelligent Systems, EarlyView.HTFC gets 3D refractive index tomograms of flowing cells. Label‐free monocytes are engineered to express patterns of cytoplasmic vacuoles. From the tomogram, an efficient dimensionality reduction is operated. Interpretable features are extracted to classify the expression severity of phenotypes coexisting in each cell, visually represented by a seven ...
Marika Valentino +9 more
wiley +1 more source
Microautophagy: current understanding of its molecular mechanisms and functions
Autophagy ReportsMicroautophagy (MI-autophagy) is an umbrella term for intracellular degradative pathways that entail the invagination or protrusion of the limiting membranes of endolysosomal compartments, that is, late endosomes and mammalian lysosomes or yeast and ...
Yasuyoshi Sakai +16 more
doaj +1 more source
Vacuole biogenesis in Arabidopsis thaliana [PDF]
, 2017 All higher plants form leaves and roots, organs specialized to efficiently absorb carbon dioxide, collect energy from the sunlight and take up water as well as minerals. These tissues usually have a large surface area made up of big cells.
Krüger, Falco
core +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Hypomethylating agents (HMA) and allogeneic hematopoietic stem cell transplantation (alloHSCT) have both demonstrated remissions in VEXAS; however, comparative data is lacking. We conducted a multicenter, retrospective analysis of 66 patients diagnosed with VEXAS syndrome treated with HMA (n = 35) or alloHSCT (n = 31). Baseline characteristics
Saubia Fathima +48 more
wiley +1 more source