Results 71 to 80 of about 425,388 (212)
The Vacuole Lipid Droplet Contact Site vCLIP
Lipid droplets frequently form contact sites with the membrane of the vacuole, the lysosome-like organelle in yeast. These vacuole lipid droplet (vCLIP) contact sites respond strongly to metabolic cues: while only a subset of lipid droplets is bound to ...
Duy Trong Vien Diep +3 more
core +1 more source
GO term of fungal-type vacuole membrane.
, 2015 Fungal-type vacuole membrane is vacuole membrane, it is the organelle membrane which belongs to cellular component. Being the largest organelles in cells of eukaryotic microorganisms, vacuoles are known to function in intracellular ion homeostasis ...
Guo-Lian Bao (723387) +5 more
core +1 more source
Advanced Science, EarlyView.PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao +8 more
wiley +1 more source
, 2019 Over the past 9 years I have worked with artists who have used various media to portray the process of autophagy. This has included paintings, protein music, a piano composition, a wood sculpture, a quilt, and a dance. Here, I describe a two-part project
Scott Hartley (6953780) +1 more
core +1 more source
Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast [PDF]
, 1999 In Saccharomyces cerevisiae, amino acid permeases are divided into two classes. One class, represented by the general amino acid permease GAP1, contains permeases regulated in response to the nitrogen source.
Hall, M. N. +5 more
core +1 more source
SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells
Animal Models and Experimental Medicine, EarlyView.The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang +6 more
wiley +1 more source
In Vivo Nb4C3Tx MXene‐Assisted Photothermal Therapy of Melanoma in Mice
Advanced NanoBiomed Research, EarlyView.Nb4C3Tx MXene converts pulsed 1064 nm irradiation into localized heat, producing concentration‐ and time‐dependent melanoma cell killing in vitro and suppressing tumor growth in mice. Histology reveals extensive tumor damage, macrophage‐associated material clearance, and no detectable persistent deposits in examined visceral organs, supporting Nb4C3Tx ...
Anton Roshchupkin +22 more
wiley +1 more source
Phase separation in yeast vacuole membranes
, 2022 Thesis (Ph.D.)--University of Washington, 2022Membranes of vacuoles, the lysosomal organelle in yeast, phase separate into two coexisting liquid phases.
Leveille, Chantelle L
core
Liver Transplantation, EarlyView., 2022 Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono +8 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract The equine ovary exhibits unique structural and developmental features that distinguish it from those of other domestic species, including the presence of an ovulation fossa and an inversion of cortical and medullary layers. This study aimed to investigate the morphostructural development of the equine fetal ovary, with particular emphasis on ...
Laura Ver Goltz +5 more
wiley +1 more source