Results 271 to 280 of about 438,290 (354)

Mapping VEXAS‐associated and rare UBA1 variants in the United Kingdom: Insights from patient cohorts and the general population

British Journal of Haematology, EarlyView.
VEXAS syndrome is a late‐onset inflammatory disorder with rheumatological and haematological features. Epidemiological studies of VEXAS syndrome so far have been limited. Analysis of various UK cohorts estimates the incidence of VEXAS to be 1.51/100 000, or 171 new cases in the population of men over the age of 50 who are being investigated for myeloid
Ana Martinez Rodriguez, Leon Chang, Dorota Rowczenio, Alexandra Smith, Ebun Omoyinmi, James A. Poulter, Andrew McGregor, Sebastian Francis, Roochi Trikha, Adam Al‐Hakim, Kar Lok Kong, David G. Kent, Helen Lachmann, Austin Kulasekararaj, Catherine Cargo, Sinisa Savic   +15 more
wiley   +1 more source

Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis.

, 1990
Lois M. Banta, Thomas A. Vida, Paul K. Herman, Scott D. Emr   +3 more
openalex   +1 more source

Seeing is believing: Whole-cell electron tomography models of vacuole morphology and formation in the early-stage root cortex of Arabidopsis. [PDF]

Plant Cell
Cui Y, Gao J, Li Y, Zhang H, Zheng X, Qi Q, Zhang S, Kang BH, Jiang L.   +8 more
europepmc   +1 more source

A short domain of the plant vacuolar protein phytohemagglutinin targets invertase to the yeast vacuole.

, 1990
Brian W. Tague, Craig D. Dickinson, Maarten J. Chrispeels   +2 more
openalex   +1 more source

S-RNase Internalisation and Vacuolar Targeting via Clathrin-Dependent Endocytosis Mediate Interspecific Pollen Rejection in Nicotiana. [PDF]

Physiol Plant
Rios-Carrasco S, García-Caffarel E, Cruz-Zamora Y, Jiménez-Díaz E, Cruz-García F.   +4 more
europepmc   +1 more source

3D imaging of neuronal inclusions and protein aggregates in human neurodegeneration by multiscale x‐ray phase‐contrast tomography

Brain Pathology, EarlyView.
x‐ray phase‐contrast tomography enabled three‐dimensional, label‐free visualization and quantification of protein aggregates in neurodegenerative diseases with isotropic submicrometer resolution. The study revealed distinct electron density patterns in Lewy bodies, Hirano bodies, granulovacuolar degeneration, and amyloid plaques, highlighting their ...
Jonas Franz, Jakob Reichmann, Marina Eckermann, Thea Würfel, Artur Groh, Syed Fatima Qadri, Katja Schulz, Brit Mollenhauer, Christine Stadelmann, Tim Salditt   +9 more
wiley   +1 more source

Astragaloside IV alleviates hypoxic pulmonary hypertension by inhibiting RELM‐β to reduce PINK1/Parkin‐mediated mitophagy in pulmonary artery smooth muscle cells (PASMCs)

British Journal of Pharmacology, EarlyView.
Background and Purpose Hypoxic pulmonary hypertension (HPH) is a chronic disorder marked by irreversible pulmonary vascular remodelling (PVR) and pulmonary artery smooth muscle cell (PASMC) dysfunction. Astragaloside IV (AS‐IV), a natural saponin from Astragalus, shows potential in HPH management. This study explores AS‐IV's protective effect on PVR in
Rongzhen Ding, Haiping Xie, Shuliu Sang, Li Qin, Yinhui Sun, Chao Zhang, Jian Yi, Hui Liu, Jianmin Fan, Guoran Peng, BeiBei Cheng, Lan Song, Aiguo Dai   +12 more
wiley   +1 more source

Clathrin-coated vesicles are targeted for selective autophagy during osmotic stress

Dragwidge JM, Buridan M, Kraus J, Kosuth T, Chambaud C, Brocard L, Yperman K, Mylle E, Vandorpe M, Eeckhout D, De Jaeger G, Pleskot R, Bernard A, Van Damme D.   +13 more
europepmc   +1 more source

Rare Auer Rods in Vacuole-Like Inclusions in Acute Promyelocytic Leukemia [PDF]

Turk J Haematol
An Z, Hao J.
europepmc   +1 more source

The tandem–random transition of cellular patterning: proposed roles of N‐cadherin‐based orientational cell adhesions in the development, maintenance, and degeneration of the nucleus pulposus

Biological Reviews, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) can contribute to lower back and neck pain. In IDD, the most affected component of the intervertebral disc is the nucleus pulposus (NP). Derived from the notochord, where cells are organized into a tandem configuration, young NP cells cluster in three‐dimensional (3D) networks embedded in a gelatinous ...
Xiangyun Wei, Nam Vo, Gwendolyn A. Sowa
wiley   +1 more source