Results 161 to 170 of about 225,485 (404)
PLoS ONE, 2011 IFN-γ is a major cytokine that mediates resistance against the intracellular parasite Toxoplasma gondii. The p65 guanylate-binding proteins (GBPs) are strongly induced by IFN-γ. We studied the behavior of murine GBP1 (mGBP1) upon infection with T. gondii
Sebastian Virreira Winter +10 more
semanticscholar +1 more source
Frontiers in Bioscience-LandmarkBackground: Cellular vacuolization is a commonly observed phenomenon under physiological and pathological conditions. However, the mechanisms underlying vacuole formation remain largely unresolved.
Dakang Sun, Xinye An, Yanli Cheng
doaj +1 more source
Legionella RavZ Plays a Role in Preventing Ubiquitin Recruitment to Bacteria-Containing Vacuoles
Frontiers in Cellular and Infection Microbiology, 2017 Bacterial pathogens like Salmonella and Legionella establish intracellular niches in host cells known as bacteria-containing vacuoles. In these vacuoles, bacteria can survive and replicate.
Tomoko Kubori +5 more
doaj +1 more source
Disruption of Toxoplasma gondii Parasitophorous Vacuoles by the Mouse p47-Resistance GTPases
PLoS Pathogens, 2005 The p47 GTPases are essential for interferon-γ-induced cell-autonomous immunity against the protozoan parasite, Toxoplasma gondii, in mice, but the mechanism of resistance is poorly understood. We show that the p47 GTPases, including IIGP1, accumulate at
Sascha Martens +6 more
semanticscholar +1 more source
Expert Perspectives on a Clinical Challenge: Hematologic Malignancies and Vasculitis
Arthritis &Rheumatology, Accepted Article.Systemic vasculitis describes a collection of rare diseases each caused by inflammation of blood vessel walls that can cause severe systemic complications [[3, 4]](#ref‐0003). The pattern of vascular inflammation and resultant damage is frequently variable and may be mimicked, or directly triggered, by infection or malignancy.
Michelle L. Robinette, Hetty E. Carraway
wiley +1 more source
Cell vacuolation induced by Haemophilus influenzae supernatants in HEp-2 cells
Memorias do Instituto Oswaldo Cruz, 2013 Haemophilus influenzae belongs to respiratory tract microbiota. We observed vacuoles formation in previous studies with H. influenzae culture supernatants, so in this work we characterised that cytotoxic effect.
Maria del Rosario Espinoza-Mellado +3 more
doaj +1 more source
Vacuoles: a hollow threat? [PDF]
Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2010 In this issue of the Journal, Bawolak et al.1 focus their studies on a mechanism that provides a provocative insight into the complexity of systems that organize the intracellular environment. This mechanism may also serve to describe the effects produced by agents that are applied in high concentrations to the outer membrane of the cell… in this case,
openaire +3 more sources
Regulation mechanisms and signaling pathways of autophagy.
Annual Review of Genetics, 2009 Autophagy is a process of self-degradation of cellular components in which double-membrane autophagosomes sequester organelles or portions of cytosol and fuse with lysosomes or vacuoles for breakdown by resident hydrolases.
Congcong He, D. Klionsky
semanticscholar +1 more source
Characteristics of weak base-induced vacuoles formed around individual acidic organelles
Folia Histochemica et Cytobiologica, 2011 We have previously found that the weak base 4-aminopyridine induces Brownian motion of acidic organelles around which vacuoles are formed, causing organelle traffic disorder in neurons.
Tadashi Kawakami, Hiromi Hiruma
doaj +1 more source
Human Reproduction, 2011 BACKGROUND The aims of this study were to establish whether individual differences exist in the frequency and size of vacuoles found in human sperm and to ascertain whether such vacuoles are involved in causing DNA damage.
Seiji Watanabe +10 more
semanticscholar +1 more source