Results 231 to 240 of about 100,485 (295)

A short domain of the plant vacuolar protein phytohemagglutinin targets invertase to the yeast vacuole.

, 1990
Brian W. Tague, Craig D. Dickinson, Maarten J. Chrispeels   +2 more
openalex   +1 more source

Astragaloside IV alleviates hypoxic pulmonary hypertension by inhibiting RELM‐β to reduce PINK1/Parkin‐mediated mitophagy in pulmonary artery smooth muscle cells (PASMCs)

British Journal of Pharmacology, EarlyView.
Background and Purpose Hypoxic pulmonary hypertension (HPH) is a chronic disorder marked by irreversible pulmonary vascular remodelling (PVR) and pulmonary artery smooth muscle cell (PASMC) dysfunction. Astragaloside IV (AS‐IV), a natural saponin from Astragalus, shows potential in HPH management. This study explores AS‐IV's protective effect on PVR in
Rongzhen Ding, Haiping Xie, Shuliu Sang, Li Qin, Yinhui Sun, Chao Zhang, Jian Yi, Hui Liu, Jianmin Fan, Guoran Peng, BeiBei Cheng, Lan Song, Aiguo Dai   +12 more
wiley   +1 more source

During <i>Aspergillus nidulans</i> nitrogen-limited biofilm formation, mitophagy is independent of mitochondrial fission. [PDF]

Autophagy Rep
Balasubramanian HK, Osmani SA.
europepmc   +1 more source

The tandem–random transition of cellular patterning: proposed roles of N‐cadherin‐based orientational cell adhesions in the development, maintenance, and degeneration of the nucleus pulposus

Biological Reviews, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) can contribute to lower back and neck pain. In IDD, the most affected component of the intervertebral disc is the nucleus pulposus (NP). Derived from the notochord, where cells are organized into a tandem configuration, young NP cells cluster in three‐dimensional (3D) networks embedded in a gelatinous ...
Xiangyun Wei, Nam Vo, Gwendolyn A. Sowa
wiley   +1 more source

Light and electron microscopy of the pharynx and gastrodermis of the monogenean gill parasite Macrogyrodactylus clarii from the catfish Clarias gariepinus (Burchell, 1822). [PDF]

Parasitol Res
El-Naggar MM, Arafa SZ, El-Abbassy SA, Cable J.   +3 more
europepmc   +1 more source

Citrullination in Tumor Metastasis, Inside and Outside the Cells

Cancer Science, EarlyView.
ABSTRACT Tumor metastasis remains a poor prognosis because it occurs in all tissues and is difficult to diagnose or prevent before metastatic tumor nodules form. Metastasis is a multi‐step process involving tumor cells, bone marrow‐derived cells, and tissue resident cells, making it a biological three‐body problem.
Takeshi Tomita, Priyanka Sharma, Sachie Hiratsuka   +2 more
wiley   +1 more source

Molecular insights into the effects of laser-induced optical breakdown (LIOB) after 1064 nm picosecond laser irradiation using a novel melanocyte-containing 3D skin model. [PDF]

Lasers Med Sci
Huth S, Marquardt Y, Huth L, Gerber PA, Baron JM.   +4 more
europepmc   +1 more source

Mechanism of EC‐EXOs‐Derived THBS3 Targeting CD47 to Regulate BMSCs Differentiation to Ameliorate Bone Loss

Cell Proliferation, EarlyView.
EC‐EXOs could regulate the differentiation of BMSCs through the key protein THBS3, which inhibits their differentiation to lipogenic cells and promotes their differentiation to osteoblasts. THBS3 could down‐regulate the expression of its downstream target CD47 and delay the process of bone loss in aged mice and OVX mice, which may provide a novel ...
Jiaojiao Wang, Zhaokai Zhou, Wenjie Chen, Yun Chen, Qiyue Zheng, Yajun Chen, Zhengxiao Ouyang, Ran Xu, Qiong Lu   +8 more
wiley   +1 more source

Organoid-based <i>in vitro</i> system and reporter for the study of <i>Cryptosporidium parvum</i> sexual reproduction. [PDF]

Microbiol Spectr
Korwin-Mihavics BR, Dews EA, Miller P, Cameron A, Martorelli di Genova B, Huston CD.   +5 more
europepmc   +1 more source

YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice

Cell Proliferation, EarlyView.
Specifically ablating Ykt6 in pre‐meiotic germ cells and meiotic spermatocytes leads to complete sterility and meiotic arrest in conditional knockout male mice. YTK6 is required for stabilising intercellular bridges between spermatocytes due to its key role in maintaining protein homeostasis and vesicular transport‐dependent functions in spermatocytes,
Jie Cen, Xiaochen Yu, Ziqi Wang, Wenbo Liu, Jianze Xu, Qian Fang, Fei Gao, Yongzhi Cao, Hongbin Liu   +8 more
wiley   +1 more source