mBioThe bacterium Listeria monocytogenes (Lm) causes listeriosis in humans and ruminants. Acute lesions are predominantly infiltrated by polymorphonuclear neutrophils (PMNs), considered to be the efficient bactericidal arm of innate immunity. However, recent
Stefano Bagatella +6 more
doaj +1 more source
Rimmed vacuoles in Becker muscular dystrophy have similar features with inclusion myopathies.
PLoS ONE, 2012 Rimmed vacuoles in myofibers are thought to be due to the accumulation of autophagic vacuoles, and can be characteristic in certain myopathies with protein inclusions in myofibers.
Kazunari Momma +7 more
doaj +1 more source
Advanced Science, EarlyView.Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka +3 more
wiley +1 more source
Alteration of SH-group Contents in Red Beet Roots and Vacuoles under Osmotic Stress [PDF]
Journal of Stress Physiology & Biochemistry, 2013 The content of sulfhydryl groups in homogenate of red beets and isolated vacuoles under the conditions of osmotic stress was determined. It was demonstrated that the common content of sulfhydryl groups in the isolated vacuoles was 2.4 times higher, than ...
Ozolina, N. V. +6 more
doaj
A substrate localization model for the selective regulation of TORC1 downstream pathways
Communicative & Integrative Biology, 2018 Target of rapamycin complex 1 (TORC1) is a protein kinase complex conserved in eukaryotes that coordinates diverse cellular processes critical for cell growth to environmental conditions.
Eigo Takeda, Akira Matsuura
doaj +1 more source
Production of the main celiac disease autoantigen by transient expression in Nicotiana benthamiana [PDF]
, 2015 Celiac Disease (CD) is a gluten sensitive enteropathy that remains widely undiagnosed and implementation of massive screening tests is needed to reduce the long term complications associated to untreated CD.
Acevedo, Gonzalo Raúl +4 more
core +2 more sources
Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions
Advanced Science, EarlyView.This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang +4 more
wiley +1 more source
The Shigella flexneri type 3 secretion system is required for tyrosine kinase-dependent protrusion resolution, and vacuole escape during bacterial dissemination. [PDF]
PLoS ONE, 2014 Shigella flexneri is a human pathogen that triggers its own entry into intestinal cells and escapes primary vacuoles to gain access to the cytosolic compartment.
Carole J Kuehl +2 more
doaj +1 more source
Stepped vitrification technique for human ovarian tissue cryopreservation [PDF]
, 2019 The advantage of stepped vitrification (SV) is avoiding ice crystal nucleation, while decreasing the toxic effects of high cryoprotectant concentrations. We aimed to test this method for human ovarian tissue cryopreservation.
Amorin, C.A. +9 more
core +1 more source
Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean
Advanced Science, EarlyView.This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma +11 more
wiley +1 more source