Results 61 to 70 of about 2,665,933 (332)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Thermodynamics of Fuzzy Spheres in PP-wave Matrix Model
, 2004 We discuss thermodynamics of fuzzy spheres in a matrix model on a pp-wave background. The exact free energy in the fuzzy sphere vacuum is computed in the \mu -> \infty limit for an arbitrary matrix size N.
Bak +23 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Is there vacuum when there is mass? Vacuum and non-vacuum solutions for massive gravity
, 2013 Massive gravity is a theory which has a tremendous amount of freedom to describe different cosmologies; but at the same time the various solutions one encounters must fulfill some rather nontrivial constraints.
Martin-Moruno, Prado, Visser, Matt
core +1 more source
Simulation of thermal and flow field in a large-scale vertical roll-to-roll PECVD chamber [PDF]
AIP AdvancesThe distribution of gas flow and temperature fields plays a crucial role in influencing the uniformity and deposition rate of PECVD (plasma enhanced chemical vapor deposition) coating deposition processes.
Xuelei Li +10 more
doaj +1 more source
Vacuum Electrodeposition of Cu(In, Ga)Se2 Thin Films and Controlling the Ga Incorporation Route
Crystals, 2023 The traditional electrochemical deposition process used to prepare Cu(In, Ga)Se2 (CIGS) thin films has inherent flaws, such as the tendency to produce low-conductivity Ga2O3 phase and internal defects. In this article, CIGS thin films were prepared under
Kanwen Hou +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
On the Vacuum Structure of the 3-2 Model
, 2012 The 3-2 model of dynamical supersymmetry breaking is revisited, with some incidentally new observations on the vacuum structure. Extra matter is then added, and the vacuum structure is further studied.
Shacham, Tomer
core +1 more source
Ground‐State Chemical Reactivity under Vibrational Coupling to the Vacuum Electromagnetic Field
Angewandte Chemie, 2016 The ground‐state deprotection of a simple alkynylsilane is studied under vibrational strong coupling to the zero‐point fluctuations, or vacuum electromagnetic field, of a resonant IR microfluidic cavity. The reaction rate decreased by a factor of up to 5.
Anoop Thomas +11 more
semanticscholar +1 more source
A Method for Optimizing Technical Parameters of the Vacuum Freeze-Drying Process [PDF]
Kemija u Industriji, 2014 Vacuum freeze-drying is a technique that makes a material dehydrate at low temperature and low pressure, and it has many merits. A control system is designed and developed based on a certain area freeze-drying machine.
Qian, X.-M., Huang, W.-R., Lou, P.-H.
doaj +1 more source