Results 51 to 60 of about 2,686,430 (333)
Movement and Fluctuations of the Vacuum [PDF]
Quantum fields possess zero-point or vacuum fluctuations which induce mechanical effects, namely generalised Casimir forces, on any scatterer. Symmetries of vacuum therefore raise fundamental questions when confronted with the principle of relativity ...
Adler R J +124 more
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
As one of the promising anode materials, iron selenide has received much attention for potassium-ion batteries (KIBs). Nevertheless, volume expansion and sluggish kinetics of iron selenide result in the poor reversibility and stability during ...
Xiaodan Li +7 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Terahertz (THz) bands are critical for next-generation wireless fronthaul/backhaul applications. However, they face a fundamental coverage range limitation due to low emission power, severe path loss, and poor receiving sensitivity, especially in ...
Yuancheng Cai +17 more
doaj +1 more source
Microfabrication Technologies for Interaction Circuits of THz Vacuum Electronic Devices
Advances in manufacturing technology are allowing for the realization of interaction circuit with microstructures. The capability to produce small circuit structures is allowing new opportunities for vacuum electronic devices producing terahertz (THz ...
Xinghui Li, Jinjun Feng
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Design and Performance Verification of a Space Radiation Detection Sensor Based on Graphene
In order to verify the performance of a graphene-based space radiation detection sensor, the radiation detection principle based on two-dimensional graphene material was analyzed according to the band structure and electric field effect of graphene.
Heng An +6 more
doaj +1 more source

