Results 61 to 70 of about 530,558 (268)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Application of multi-stage vacuum distillation for secondary resource recovery: potential recovery method of cadmium telluride photovoltaic waste

Journal of Materials Research and Technology, 2020
With the widespread use of cadmium telluride solar cells, environmental protection, and effective recycling approaches for solar cell component waste have become topics of concern.
Xiaofeng Zhang, Dachun Liu, Wenlong Jiang, Wenjie Xu, Pan Deng, Juhai Deng, Bin Yang   +6 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Simulation analysis of radiometer effect and outgassing based on molecular particle source perturbation

Scientific Reports
The Laser Interferometer Space Antenna (LISA) mission is designed to detect space gravitational wave sources in the millihertz band. A critical factor in the success of this mission is the residual acceleration noise metric of the internal test mass (TM)
Wenyan Zhang, Zuolei Wang, Jian Min, Yi Wang, Jungang Lei, Yunpeng Li, Dongxue Xi   +6 more
doaj   +1 more source

Finite Element Analysis of Electrostatic Coupling in LISA Pathfinder Inertial Sensors

Sensors
In the LISA Pathfinder (LPF) mission, electrostatic noise can reach the femto-Newtonian level despite the fact that the LPF’s sensors are equipped with potential shielding.
Wenyan Zhang, Jungang Lei, Zuolei Wang, Cunhui Li, Shijia Yang, Jian Min, Xuan Wen   +6 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Research on High-Precision and Wide-Range Spacecraft Potential Measurement Method Based on Capacitive Voltage Division

Sensors
The charging and discharging of satellite surfaces induced by the space plasma environment constitute a primary cause of spacecraft anomalies, particularly in geosynchronous orbits subject to geomagnetic substorms and hot plasma injections from the ...
Hong Yin, Haibo Liu, Xiaogang Qin, Qing Liu, Jun Wang, Xuan Wen, Peng Wang, Zixin Yu, Shengsheng Yang   +8 more
doaj   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Nano-Pigment Cr₂O₃ Preparation from Chromium Slag by Alkaline Roasting, Water Leaching, Glucose Reduction and Vacuum Calcination

Metals
Metallurgical chromium slag is a hazardous by-product generated during the production of chromium salts and metallic chromium, containing significant amounts of leachable Cr(VI), which poses severe environmental and human health risks.
Huiwen Li, Zhe Gao, Shaoxiong Li, Haocheng Qin, Qianfang Yan, Zhaowang Dong, Xiangfeng Kong, Bin Yang, Hongwei Yang   +8 more
doaj   +1 more source