Results 31 to 40 of about 549,979 (269)
Astrophysics and Space Science, 2006 8 ...
Burdyuzha, Vladimir, Vereshkov, Grigoriy
openaire +2 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Numerical simulation and experimental research of LRIT-30 radio frequency ion thruster
AIP Advances, 2021 This study aimed at discussing the laws of the design parameters of a radio frequency (RF) ion thruster that influence the thruster performance, guide the performance optimization-oriented design of the thruster, and realize the high-accuracy continuous ...
Yanxu Pu +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Light: Science & ApplicationsTerahertz (THz) bands are critical for next-generation wireless fronthaul/backhaul applications. However, they face a fundamental coverage range limitation due to low emission power, severe path loss, and poor receiving sensitivity, especially in ...
Yuancheng Cai +17 more
doaj +1 more source
A torsional thrust stand for electric propulsion thruster [PDF]
AIP AdvancesA torsional thrust stand with heavy load and stability has been developed for electric propulsion thruster testing under vacuum conditions. The thrust measurement principle is based on torsional pendulum mechanics combined with capacitive displacement ...
H. Zhang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Microfabrication Technologies for Interaction Circuits of THz Vacuum Electronic Devices
MicromachinesAdvances in manufacturing technology are allowing for the realization of interaction circuit with microstructures. The capability to produce small circuit structures is allowing new opportunities for vacuum electronic devices producing terahertz (THz ...
Xinghui Li, Jinjun Feng
doaj +1 more source
Metals, 2018 The compound CaCl2 plays a significant role in the process of direct calciothermic reduction of Ti2O3 to prepare porous titanium. In this paper, the effect of CaCl2 on reduction products by calciothermic reduction of Ti2O3 was investigated.
Guobo Yang +5 more
doaj +1 more source