Results 111 to 120 of about 169 (166)

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

open access: yesAdvanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie   +20 more
wiley   +1 more source

Metal Ion‐Induced Fast Gelation of 2D MnO2 Nanosheets With Cationic Vacancies for Durable Aqueous Zinc‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
We report Mn‐deficient aerogels by inducing the first gelation of MnO2 nanosheets in solution using divalent metal ions as crosslinking agents, thereby inhibiting nanosheet restacking and enhancing surface utilization. Benefiting from abundant Mn vacancies and 3D porous structures, the A‐MnO2 cathode exhibits improved conductivity, fast reaction ...
Yalei Wang   +6 more
wiley   +1 more source

Programmable Multi‐Axially Aligned Aerogels via Sequential Freeze‐Casting for Tailored Anisotropy and Tunable Mechanics

open access: yesAdvanced Science, EarlyView.
Conventional single‐gradient freeze‐casting typically produces unidirectional porous architectures with limited transverse connectivity. The Sequential Hybridization by Infiltration and Freeze‐casting Technique (SHIFT) addresses this constraint by integrating secondary aligned structures within a preformed primary scaffold.
Kiho Sung, Sungchul Shin
wiley   +1 more source

Optimizing Stratification in Binary Colloidal Supraparticles

open access: yesAdvanced Science, EarlyView.
Supraparticles from binary particle populations show stratification when dried at high Péclet numbers. In spray‐dried systems at high initial particle concentration and fast drying conditions optimal combinations of particle size ratios and volume fractions that produce maximal stratification are found both in experiment and simulation, contrasting the
Frederic Rudlof   +5 more
wiley   +1 more source

Recent Advances in Carbon Cathode Materials toward High‐Performing Zinc‐Ion Hybrid Supercapacitors

open access: yesAdvanced Science, EarlyView.
Aqueous zinc‐ion hybrid supercapacitors (ZHSCs) have emerged as promising next‐generation electrochemical energy‐storage devices. Porous carbon materials have been extensively studied as cathodes, with advances in tailoring pore structures and material properties to enhance performance.
Take Hirooka   +3 more
wiley   +1 more source

Targeted Delivery of Indole‐3‐Pyruvic Acid Suppresses Macrophage Ferroptosis to Enhance CD8+ T Cell‐Mediated Immunotherapy Response in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
A microbiota‐derived metabolite, indole‐3‐pyruvic acid, suppresses macrophage ferroptosis through the AHR–NF‐κB–SLC7A11 axis. This preserves CD8+ T cell function in bladder cancer. Macrophage‐targeted nanoparticles enhance indole‐3‐pyruvic acid delivery and overcome resistance to PD‐1 blockade.
Jianwen Lao   +15 more
wiley   +1 more source
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Sublimation Freeze-Drying without Vacuum

Science, 1959
Analysis of the freeze-drying procedure shows that the passage of water vapor from the drying boundary through the dried shell is facilitated primarily by the vapor pressure gradient rather than by the absolute pressure of the system. This is experimentally confirmed, and a device for freeze-drying at atmospheric pressure is described.
openaire   +3 more sources

Rapid vacuum freeze‐drying of meat

Journal of the Science of Food and Agriculture, 1958
AbstractFreeze‐drying carried out in conventional equipment is a slow process, the rate of drying being limited by the rate of transfer of heat of sublimation. A method is described to carry out rapid freeze‐drying of meat or other foodstuffs by laying the pieces between heater plates fitted with metal spikes which conduct heat uniformly and ...
C. Brynko, W. R. Smithies
openaire   +1 more source

Freeze‐drying using vacuum‐induced surface freezing

Journal of Pharmaceutical Sciences, 2002
A method of freezing during freeze-drying, which avoids undercooling of a solution and allows growth of large, dendritic ice crystals, was investigated. Aqueous solutions of mannitol, sucrose, or glycine were placed under a chamber vacuum of approximately 1 mbar at a shelf temperature of +10 degrees C.
Martin, Kramer   +2 more
openaire   +2 more sources

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